Bioavailability of Potassium From Potatoes and Potassium Gluconate

Blood Pressure Clinical Trial

— Potato  

Official title:

Bioavailability of Potassium From Potatoes and Potassium Gluconate

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01881295
• Other study ID #: 1301013174
• Status: Completed
• Phase: N/A
• Start date: March 1, 2013
• Est. completion date: December 2014

Study information

• Verified date: May 2018
• Source: Purdue University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study is designed to compare the effect of sources of potassium on uptake and the effect of potassium on blood pressure.

Description:

The study will compare uptake of potassium from three different doses and sources; supplements (720, 1440 and 2160 mg) potatoes (720, 1440 and 2160 mg) or French fries (2160 mg).

During 9 phases, participants will consume a controlled diet with the supplements, potato or french fries (every other week for 5 days). On the 4th day, blood and urine samples will be taken to monitor potassium uptake and excretion. Measures of blood pressure will be analyzed at defined time points throughout the intervention.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 45
• Est. completion date: December 2014
• Est. primary completion date: August 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

• Able to adhere to the visit schedule, protocol requirements and available to complete the study

• Normotensive men and women

• Aged 20-60 years

• BMI of 15-35

Exclusion Criteria:

• Medication to treat hypertension or hypotension

• Medication known to affect electrolyte metabolism or contain high levels of potassium or sodium

• smoke cigarettes or use illegal drugs

• Hypertension or hypotension

• Diseases known to affect potassium metabolism

• Pregnant

• Allergic to nuts

Related Conditions & MeSH terms

• Blood Pressure
• Potassium Bioavailability

Intervention

Dietary Supplement:
• Placebo control

• Low dose potassium gluconate

• Medium dose potassium gluconate

• High dose potassium gluconate

• Low dose potato

• Medium dose potato

• High dose potato

• High dose French fries

• Basal diet control

Locations

Country	Name	City	State
United States	Purdue University	West Lafayette	Indiana

Sponsors (2)

Lead Sponsor	Collaborator
Purdue University	Alliance for Potato Research and Education (APRE)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Bioavailability of Potassium	After 4 days of acclimation to the supplementation, absorption of potassium will be measured.	5 days
Secondary	Blood Pressure Response to Potassium	Differences in blood pressure will be measured between levels of potassium consumption.	6 days