The Impact of Hospitalization on Ambulatory Blood Pressure and Intraocular Pressure

Blood Pressure Clinical Trial

Official title:

A Study Investigating the Impact of Hospitalization on Ambulatory Blood Pressure and Intraocular Pressure in Subjects With Mild to Moderate Arterial Hypertension and Untreated Ocular Hypertension

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01029860
• Other study ID #: A3244
• Status: Completed
• Phase: N/A
• First received: December 9, 2009
• Last updated: December 16, 2009
• Start date: March 2007
• Est. completion date: March 2009

Study information

• Verified date: March 2007
• Source: Aristotle University Of Thessaloniki
• Contact: n/a
• Is FDA regulated: No
• Health authority: Greece: Ethics Committee
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to assess the effect of hospital admission on 24-hour ambulatory blood pressure (ABP) in hypertensive subjects.Treated or untreated hypertensive adults with open angle glaucoma underwent in-hospital and outpatient 24-hour ABP monitoring, in random order 4 weeks apart.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: March 2009
• Est. primary completion date: January 2009
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 30 Years to 65 Years

Eligibility

Inclusion Criteria:

• age >30 years old.

• subject has signed an informed consent.

• patient has untreated ocular hypertension (IOP at 10:00 between 22-34 mm Hg)

• patient has stage 1 arterial hypertension with or without therapy

Exclusion Criteria:

• secondary hypertension.

• stage 2 or 3 hypertension, history of renal disease.

• sleep apnea.

• diabetes mellitus

• acute or chronic inflammation.

• myocardial infarction or unstable angina within the past 6 months.

• heart failure NYHA class III-IV.

• active liver disease.

• pregnancy.

• history of drug or alcohol abuse, or any other condition with poor prognosis.

• treatment with non-steroid anti-inflammatory agents, corticosteroids, beta-blockers, or any other regimen that could affect BP levels.

• smoking

Study Design

Observational Model: Case-Crossover, Time Perspective: Prospective

Related Conditions & MeSH terms

• Blood Pressure

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Aristotle University Of Thessaloniki