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Clinical Trial Summary

Damages in frontal area present in neurodegenerative disease (frontotemporal degeneration, frontal variant of Alzheimer disease) and in psychiatric disease (bipolar disorder) can affect behavior and cognition including social cognition. Symptoms vary both quantitatively and qualitatively from disease to another and from person to person. It cannot be completely excluded that in some cases, factors of susceptibility such as premorbid personality traits lead to frontal fragility. The study will assess the relationship between premorbid profile using NEO-PI 3 inventory and cognitive and behavioral/psychobehavioral manifestations in patients with behavioral variant of frontotemporal disorder (bvFTD), phenocopy frontotemporal dementia (phFTD), frontal variant of Alzheimer disease, bipolar disorder characterized with frontal damages.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06059313
Study type Observational
Source Nantes University Hospital
Contact Claire BOUTOLEAU-BRETONNIERE, PH
Phone 33 2 40 16 54 22
Email claire.boutoleaubretonniere@chu-nantes.fr
Status Not yet recruiting
Phase
Start date October 1, 2023
Completion date February 1, 2027

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