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Reward and Punishment Sensitivity in Bipolar Disorders — Recodec-BP  

Bipolar Disorder Clinical Trial

Official title:
Reward and Punishment Sensitivity in Bipolar Disorders

Clinical Trial Summary

Bipolar disorder (BD) represents a chronic mood disorder and one of the leading causes of disability worldwide. Complexity of its clinical presentations leads to delayed diagnosis and difficult management in routine clinical settings. Whereas distinguishing BD-I and BD-II main subtypes has a significant relevance for treatment strategy and for outcome, there are currently no clinical determinants of the BD subtype which could be used as early diagnostic predictors.

- While neurobiological specificity of each BD subtype is still controversial, available evidence suggest different dopaminergic abnormalities in each subtype. Dopaminergic function is involved in decision making and reward processing which may represent useful BD subtype markers.

- This study aims at assessing decision making during appetitive and punitive reinforcement learning in patients with BD I and BD II subtypes compared to healthy controls

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04237610
Study type Observational
Source University Hospital, Grenoble
Contact Mircea POLOSAN, MD, PhD
Phone 0033476765414
Email mpolosan@chu-grenoble.fr
Status Recruiting
Phase
Start date February 24, 2020
Completion date February 23, 2022
View Details
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