Illness Representations in Patients With Bipolar Disorders

Bipolar Disorder Clinical Trial

— RsBiP  

Official title:

Illness Representations in Patients With Bipolar Disorders. What Mecanisms and What Impacts on Adherence and Quality of Life ?

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03595670
• Other study ID #: 2017-55
• Status: Recruiting
• Start date: April 11, 2018
• Est. completion date: October 2020

Study information

• Verified date: July 2018
• Source: Assistance Publique Hopitaux De Marseille
• Contact: raoul BELZEAUX, MD
• Phone: +33 491744082
• Email: raoul.belzeaux[@]ap-hm.fr
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Bipolar disorder is a serious and chronic illness representing a major health problem with high mortality rates. According to the self-regulation model , patients had some representations of their illness which are cognitive and emotional. Cognitive representations include the set of beliefs built around the illness, its consequences and treatment. Emotional representations are negative emotions generated by the presence of the illness. According to Leventhal et al. (1997), representations are linked to information extracts by patients from society, relatives, experiences. This model has been particularly studied in the context of somatic disorders, but Baines & Wittkowski (2013) shown that it may also be relevant in patients with mental disorders. In bipolar disorders, first results show that illness representations are related to relapses and to medication adherence. That's why, we think that this relevant to improve knowledges of the psychological processes that accompany the experience of bipolar disorders. To assess illness representation, we will use both qualitative and quantitative tools. These results could have direct application to clinical practice in psychosocial interventions.

Description:

Bipolar disorder is a serious and chronic illness representing a major health problem with high mortality rates (Colom and Lam, 2005). According to the self-regulation model (Leventhal, Nerenz & Steel, 1986), patients had some representations of their illness which are cognitive and emotional. Cognitive representations include the set of beliefs built around the illness, its consequences and treatment. Emotional representations are negative emotions generated by the presence of the illness. According to Leventhal et al. (1997), representations are linked to information extracts by patients from society, relatives, experiences. This model has been particularly studied in the context of somatic disorders, but Baines & Wittkowski (2013) shown that it may also be relevant in patients with mental disorders. In bipolar disorders, first results show that illness representations are related to relapses (Lobban et al., 2013) and to medication adherence (Averous, Charbonnier, Lagouanelle-Simeoni, Prosperi & Dany, 2018). That's why, we think that this relevant to improve knowledges of the psychological processes that accompany the experience of bipolar disorders. To assess illness representation, we will use both qualitative and quantitative tools. These results could have direct application to clinical practice in psychosocial interventions.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: October 2020
• Est. primary completion date: April 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

• Men or women whose is between 18 and 85 years

• Patients diagnosed bipolar in mania, depression or euthymic phases according DSM-IV critiera by psychiatrist

• Taking in charge in the framework of service Psychiatrie Secteur 5 - Hôpitaux Sud - Hôpital Sainte Marguerite de Marseille

• Patients agreeing to participate to study

Exclusion Criteria:

• Minor patients or over 85 years old

• Patients not understanding French

• Patients with neurological or psychiatric disorders prohibiting their comprehension of the study

• Patients deprived of their liberty following a judicial or administrative decision

• Patients supported without their consent

• Patients under legal guardianship

• Patients treated in emergencies

• Patients refusing to participate in the study

Related Conditions & MeSH terms

• Bipolar Disorder
• Disease

Intervention

Other:
• standardized questionnaires
standardized questionnaires concerning the perception
• interview
Semi-directive interviews will be conducted. The purpose of this approach is to question the meaning of the disease (beliefs, representations), the psycho-social management of the disease, its inscription in the socio-cultural condition of the patients.

Locations

Country	Name	City	State
France	Assistance Publique Des Hopitaux de Marseille	Marseille	Paca

Sponsors (1)

Lead Sponsor	Collaborator
Assistance Publique Hopitaux De Marseille

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Illness perception for schizophrenia (IPQS)	IPQS in an autoquestionnaire evaluating illness representations according to the self-regulation model.	24 hours
Secondary	Illness Perception Questionnaire Bref (IPQ-B)	IPQ-B evaluate similar dimensions from IPQ-S in only once item.	24 hours
Secondary	Qualitative study of illness perceptions	Measure of illness representations according to the self-regulation model evaluated with a semi-structured interview.	24 hours