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Clinical Trial Summary

Analysis of 4 CSF Alzheimer's disease biomarkers (total and phosphorylated tau protein, Aß40 and Aß1-42) and morphological brain MRI in older patients (>60 year's old) with bipolar disorder, after an evaluation of their cognitive functions.

Comparison between two groups of patients : patients with cognitive disorders and patients without cognitive disorders.

The objective is to describe and compare the profile of those biomarkers in those two populations.


Clinical Trial Description

Describe the profile of the 4 neurodegeneration's biomarkers of Alzheimer's disease dosed in the cerebrospinal fluid (Total Tau proteins, phosphorylated, Aß40 and Aß1-42) for old subjects suffering from bipolar disorder with or without cognitive impairment. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02836054
Study type Interventional
Source University Hospital, Grenoble
Contact Lora COHEN
Phone 0476765790/0476769284
Email LCohen@chu-grenoble.fr
Status Recruiting
Phase N/A
Start date November 2013
Completion date December 2019

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