Bipolar Disorder Clinical Trial
Official title:
Neuropsychological Characterization of Patients With Bipolar Disorder and a History of Suicide Attempt
The main objective of this study is to evaluate decision-making using the Iowa Gambling Task (IGT) among patients with euthymic bipolar disorder according to their personal history of suicide attempt ("suicidal" vs. "not suicidal ").
The secondary objectives of this study are:
A. Evaluate other aspects of cognitive functioning (using the Tower of London, the
Probabilistic Reversal-learning task, the Rey Complex Figure, the Reading the Mind in the
Eyes test) in euthymic patients with bipolar disorder, depending on the presence or absence
of a history of suicide attempt; B. Explore performance on neuropsychological tests
depending on the type of therapy administered (lithium salts or valproate monotherapy or in
combination with other mood stabilizers); C. Explore a possible relationship between
circulating levels of lithium or sodium divalproex results and different neuropsychological
tests; D. Establishment of a biobank for this population with leftover blood samples
following serum lithium or divalproex testing.
;
Observational Model: Cohort, Time Perspective: Cross-Sectional
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