Racing and Crowded Thoughts in Mood Disorders

Bipolar Disorder Clinical Trial

Official title:

Psychopathological and Cognitive Mechanisms of Racing and Crowded Thoughts in Mood Disorders

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02036606
• Other study ID #: 5582
• Status: Recruiting
• Start date: April 2014
• Est. completion date: April 2020

Study information

• Verified date: August 2018
• Source: University Hospital, Strasbourg, France
• Contact: Dimitri Sanchez
• Email: drci[@]chru-strasbourg.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Racing thoughts relate to subjective acceleration of thinking which has been essentially associated with manic episodes in bipolar disorder. Qualitatively, the phenomenology of racing thoughts in major depression seems to differ from rumination and pure manic racing thoughts: thoughts of all kinds accumulate in the patient's head. Recent qualitative evidence is consistent with the existence of these two kinds of "thought overactivity" related to mood disorders. In order to evaluate this and better understand the psychopathological and cognitive mechanisms that underlie thought overactivity in mood disorders, we have created a 34-item self-questionnaire - the Racing and Crowded Thoughts Questionnaire (RCTQ) and a number of neuropsychological tasks (time perception, cognitive flexibility). Also, given the relationship between mood disorders and creativity, it is likely that thought overactivity is related to increased creativity. We aim at evaluating this relationship through the French version of the Cognitive Processes Associated with Creativity scale (CPAC).

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 220
• Est. completion date: April 2020
• Est. primary completion date: April 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Bipolar disorder or depressive disorder

• 18 -65 years old

Exclusion Criteria:

• neurological conditions or sequelae

• substance abuse in the last 10 months

• schizophrenia

• ADHD

• Borderline personality disorder

• Pregnant women- Subjects under legal supervision

Related Conditions & MeSH terms

• Bipolar Disorder
• Disease
• Mood Disorders

Intervention

Behavioral:
• questionary

Locations

Country	Name	City	State
France	Service de psychiatrie 2 , Les Hôpitaux Universitaires de Strasbourg	Strasbourg	Alsace

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Validation of the French version of the scale Cognitive Processes Associated with Creativity or CPAC scale (scale that assesses creativity)		one week
Primary	Validation of the scale of Crowded Racing Thoughts Questionary = (RCTQ scale that assesses the two forms of racing thoughts)	Demonstrated a two-factor structure (crowded and racing) assessment concurrent and discriminant validity.	one week
Secondary	Evaluation of executive and temporal mechanisms involved in racing thoughts		one week