Bipolar Disorder Clinical Trial
Official title:
Parents With Bipolar Disorder: Relationship of Adaptation to Own Illness With Risk Perception and Coping With Perceived Risk to a Child
Verified date | June 7, 2013 |
Source | National Institutes of Health Clinical Center (CC) |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Background:
- Bipolar disorder is a common mood disorder that affects 1% to 2% of the population.
Individuals with bipolar disorder tend to have periods of mania that are characterized
by extra energy, very poor judgment or unrealistic beliefs about their thoughts and
abilities, and an inability to complete thoughts and tasks; as well as major depressive
episodes. The range and frequency of symptoms in affected individuals can vary greatly.
Most individuals have cyclical symptoms and spend more time in a normal mood state than
in an overtly symptomatic state.
- Relatives of individuals with bipolar disorder have an increased risk for bipolar
disorder and other mood disorders. Currently, risk assessment for recurrence of a mood
disorder is based on family and medical histories; genetic testing has not proved
particularly useful to date for assessing risks of a mood disorder.
- Despite its prevalence, there is limited research on coping with bipolar illness. No
published studies have examined adaptation to living with bipolar disorder or risk for
bipolar disorder. More specifically, though a positive family history is the most
important known risk factor for bipolar disorder, there are no published studies about
response to the threat of future illness onset in children, risk modification efforts
undertaken by affected parents, or coping with the risk for illness in children.
Objectives:
- To examine parents appraisals of the impact and cause of bipolar disorder, and the
association with their perceived risk for bipolar illness in their child and how they
cope with their perception of risk to their child.
- To assess whether parents adaptation to their own illness is associated with coping with
perceived risk to their child.
- To describe parents coping strategies related to perceived risk in their children.
Eligibility:
- Men and women at least 18 years of age who have been diagnosed with bipolar disorder and
who have at least one biological child (30 years of age or younger). Participants must be a
primary caregiver for their children.
Design:
- Participants in this study will take an online survey and answer questions about disease
perceptions, coping strategies, and adapting to a diagnosis of bipolar disorder,
addressing issues such as the following:
- Assessing the threat of bipolar disorder and coping with one s own illness.
- Optimism/pessimism of the individual coping with the illness.
- Perception of risk to a child, and coping with the perceived risk.
- Data from this study will not be shared with the participants/respondents.
Status | Completed |
Enrollment | 266 |
Est. completion date | June 7, 2013 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 90 Years |
Eligibility |
- INCLUSION CRITERIA: - Have a diagnosis of bipolar disorder - Be 18 years or older - Be a biological parent of a child who is younger than 30 years old - Be willing to participate in the survey - The participant must be (or must have been) the primary caretaker for his or her child. EXCLUSION CRITERIA: - A participant must meet inclusion criteria. - A participant s child cannot have been diagnosed with a mood disorder or other serious psychiatric disorder. - A participant s child cannot have been adopted. - The participant s child cannot be 30 years of age or older. |
Country | Name | City | State |
---|---|---|---|
United States | NAMI Research Institute | Bethesda | Maryland |
United States | National Human Genome Research Institute (NHGRI), 9000 Rockville Pike | Bethesda | Maryland |
Lead Sponsor | Collaborator |
---|---|
National Human Genome Research Institute (NHGRI) |
United States,
Austin JC, Smith GN, Honer WG. The genomic era and perceptions of psychotic disorders: genetic risk estimation, associations with reproductive decisions and views about predictive testing. Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 5;141B(8):926-8. — View Citation
Broadbent E, Petrie KJ, Main J, Weinman J. The brief illness perception questionnaire. J Psychosom Res. 2006 Jun;60(6):631-7. — View Citation
Carver CS. You want to measure coping but your protocol's too long: consider the brief COPE. Int J Behav Med. 1997;4(1):92-100. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Adaptation to bipolar disorder. | |||
Secondary | Coping with perceived risk of bipolar to ones children. |
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