Bipolar Disorder Clinical Trial
Official title:
Personal Adherence Evaluation of Individuals Receiving Treatment for Bipolar Disorder (PAE in BD)
This study will attempt to increase understanding of why bipolar disorder patients do or do not take their medications by conducting in-depth interviews with them.
Disruptive manic and depressive episodes prevent bipolar disorder (BPD) sufferers from
living healthy, functional lives. Relapse rates for BPD are high, between 70% and 90%, with
approximately half of those relapses occurring in the first 2 years after remission. High
rates of relapse and no substantial improvements in illness outcomes for many patients
despite advances in drug treatment may be related to a common problem: medication
nonadherence. Nine in 10 individuals with BPD have seriously considered medication
withdrawal, and one third of individuals with BDP do not take 30% or more of their
prescribed medications. The researchers in this study will identify BPD patients who do not
take their medications as prescribed and conduct interviews with them. By obtaining an
understanding of subjective reasons for medication nonadherence, this study will pave the
way for better interventions to ensure BDP patients take the medications that will help
them.
Participation in this study will consist of a single visit, lasting between 1.5 and 3 hours.
All participants will have a history of medication nonadherence. Participants will be asked
to fill out questionnaires and undergo a structured interview with a researcher. The
interview will be audio recorded. The questionnaires and interview will assess BPD symptoms,
attitudes toward medications, and to what extent patients are taking their medications.
Researchers will also measure the number of pills used in participants' prescriptions by
counting how many pills are left in each prescription bottle.
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