A Study of the Association Between Tobacco Smoking and Bipolar Affective Disorder

Bipolar Disorder Clinical Trial

Official title: Association Between Tobacco Smoking and Bipolar Affective Disorder.Clinico-epidemiological, Cross-sectional, Retrospective Study.

Status Completed

Clinical Trial Summary

The purpose of this study is to examine whether tobacco smoking is associated with bipolar affective disorder (severity of depressive and manic symptoms, presence of psychotic symptoms, history of a suicide attempts and other clinical features.)

Clinical Trial Description

An association exists between smoking and schizophrenia, independent of other factors and related to psychotic symptomatology. Only a few small descriptive studies have examined the prevalence and correlates of tobacco use among bipolar patients with conflicting results. Patients who smoke score higher on rating scales for psychotic symptoms than their non-smoking peers. While the association of smoking with psychotic symptomatology in schizophrenia is established, such association according to bipolar affective disorder has been reported in a few studies and remains unclear. Also a few studies reported about association of smoking with depressive and manic symptoms, and with suicidal behavior in bipolar patients. Thus further investigation of these issues is warranted. ;

Study Design

Time Perspective: Retrospective

Related Conditions & MeSH terms

• Bipolar Disorder
• Genetic Diseases, X-Linked
• Mood Disorders

• NCT number: NCT00741299
• Study type: Observational
• Source: Tirat Carmel Mental Health Center
• Status: Completed
• Phase: N/A
• Start date: August 2007
• Completion date: September 2009