Basic Science Clinical Trial
Official title:
Neural Basis of Sensory and Motor Learning: Functional Connections
The purpose of this study is to understand how the sensory and motor areas of the brain work together to keep a person's hand movements accurate (sensorimotor learning). The investigators hope this information may be useful one day to improve rehabilitation techniques in patients with brain lesions.
Status | Recruiting |
Enrollment | 120 |
Est. completion date | December 2025 |
Est. primary completion date | December 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 45 Years |
Eligibility | Inclusion Criteria: - Ages of 18-45 years old - Right-handed. - Free of Covid symptoms in week preceding testing. Exclusion Criteria: - metallic, mechanical, or magnetic implants; - are claustrophobic, or are unable to remain still for long periods of time; - use an intra-uterine device (IUD) whos MR compatibility has not been established. - Women who are pregnant or think they might be pregnant will also be excluded, as effects of fMRI on the unborn are not known. - People who have a BMI over 30 will be excluded as it may be uncomfortable or impossible to lay in the MRI scanner and reach the button box. - Potential subjects will be excluded if they have any neurological disorders, or orthopedic or pain conditions in the upper limbs. - Investigators will also exclude subjects who do not have normal vision, or corrected-to-normal vision with contacts, or the imaging center does not have a pair of MRI compatible glasses that fits their prescription. - investigators will invite subjects to reschedule if they have any of the common Covid symptoms within the last week and if they haven't been fully vaccinated or obtained a negative Covid test within the past 4 days. If they don't believe they can meet these criteria on another date, they will be excluded. - After giving their consent, participants may be excluded during the study if they are unable to perform the tasks or follow instructions. |
Country | Name | City | State |
---|---|---|---|
United States | Indiana University Bloomington | Bloomington | Indiana |
Lead Sponsor | Collaborator |
---|---|
Indiana University | National Institute of Neurological Disorders and Stroke (NINDS) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Resting state functional connectivity | Brain activity measured during a 12 minute functional magnetic resonance imaging (fMRI) scan while the subject is at rest. | 1 day | |
Primary | Reaching task performance | Measured by where the subject points on a touchscreen when reaching to the targets. | 1 day |
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