Study of Photodynamic Therapy (PDT) Using HPPH in Barrett's Esophagus

Status Completed

Clinical Trial Summary

A Study to identify toxicity and optimal photodynamic treatment parameters using the photosensitizer 2-[1-hydroxyethyl]-2-devinylpyropheophorbide-a (HPPH) in high grade dysplasia, carcinoma-in-situ, or early adenocarcinoma in Barrett's esophagus.

Clinical Trial Description

n/a

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01236443
Study type	Interventional
Source	Roswell Park Cancer Institute
Contact
Status	Completed
Phase	Phase 1
Start date	August 2000
Completion date	April 2013

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT02864043` - Barrett's Dysplasia Detection Pilot Trial Using the NvisionVLE® Imaging System	N/A
Recruiting	`NCT02018367` - Accuracy, Yield and Clinical Impact of a Low-Cost HRME in the Early Diagnosis of Esophageal Adenocarcinoma	Phase 2
Terminated	`NCT01572987` - Endoscopic Resection or Ablation for Patients With Dysplasia or Cancer Requiring Treatment of Barrett's Esophagus	N/A
Terminated	`NCT01976351` - Imaging Enhanced Endoscopy for the Screening of Barrett's Esophagus	N/A
Terminated	`NCT00526786` - Study of CryoSpray Ablation of Low Grade or High Grade Dysplasia Within Barrett's Esophagus	Phase 4
Completed	`NCT01401699` - Optical Coherence Tomography (OCT) Based Screening of Esophagus and Gastroesophageal Junction	N/A
Completed	`NCT02106910` - Non-Endoscopic Surveillance for Barrett's Esophagus Following Ablative Therapy	N/A
Suspended	`NCT01580631` - Narrow Band Imaging Project on Barrett's Esophagus
Completed	`NCT01439633` - Optical Frequency Domain Imaging (OFDI) Surveillance and Image Guided Biopsy of the Esophagus	N/A
Completed	`NCT02879721` - Expression and Function of the Renin-Angiotensin System in the Esophagus	Phase 0
Completed	`NCT01439594` - Optical Frequency Domain Imaging (OFDI) Assessment in Radiofrequency Ablation	N/A
Completed	`NCT01281618` - Influence of Acid Reflux on Stromal Epithelial Interaction in Barrett's Esophagus	N/A
Completed	`NCT00844077` - Preliminary Longitudinal Validation of Biomarkers Predictive of Barrett's Esophagus	N/A
Completed	`NCT00586872` - Endoscopic Mucosal Resection (EMR) in Barrett's Esophagus
Completed	`NCT00588575` - Ramanspectroscopy in Barrett's Esophagus
Recruiting	`NCT00288119` - Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma
Completed	`NCT02579460` - Reflux-Induced Oxidative Stress in Barrett's Esophagus: Response, Repair, and Epithelial-Mesenchymal-Transition	N/A
Completed	`NCT03813381` - CAlorie and Protein REstriction PROgram in Barrett's Esophagus Patients (CARE-PRO).	N/A
Completed	`NCT01961778` - Comparison of Treatments for Barrett's Esophagus With High-Grade Dysplasia/Early Adenocarcinoma	N/A
Not yet recruiting	`NCT02033070` - Patient Registry: Radio Frequency Ablation of Barrett's Esophagus Using HALO System	N/A