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Effect of Passive Ultrasonic Irrigation on Bacteria That Persist After Root Canal Preparation

Bacterial Infections Clinical Trial

Official title:
Effect of Passive Ultrasonic Irrigation on Bacteria That Persist After Root Canal Preparation in Teeth With Apical Periodontitis

Clinical Trial Summary

This study aims to evaluate the effectiveness of ultrasonic irrigation in improving root canal disinfection after chemomechanical procedures.

Clinical Trial Description

Although chemomechanical procedures promote a drastic bacterial reduction, many root canals remain infected, which points to the need for complementary procedures to improve root canal disinfection. Thus, this clinical study aims to evaluate the effect of passive ultrasonic irrigation as a supplementary disinfection procedure after root canal preparation. Microbiological samples of the root canals of 30 single-rooted teeth with apical periodontitis will be taken at different stages of the endodontic treatment: before preparation (S1), after chemomechanical procedures (S2) and after passive ultrasonic irrigation (S3). The samples will be submitted to the quantitative polymerase chain reaction for bacterial quantification and to the reverse transcription quantitative polymerase chain reaction for bacterial activity analysis. Data will be analyzed using the Wilcoxon test for paired samples (p < 0.05). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05100433
Study type Interventional
Source University of Sao Paulo
Contact
Status Completed
Phase N/A
Start date March 5, 2018
Completion date November 25, 2022
View Details
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