Bacterial Infections Clinical Trial
Official title:
Evaluation of Two Type III GBS Polysaccharide-Tetanus Toxoid Conjugate Vaccines
The purpose of this study is to test the safety and favorable immune response to an
anti-streptococcal vaccine (a vaccine that treats a common bacterial infection) in healthy
non-pregnant women.
Group B Streptococcus (GBS) continues to be the single most frequent cause of
life-threatening bacterial infection during the first 2 months of life. Further, GBS
pregnancy-related morbidity afflicts more than 50,000 women annually in the US. Therefore,
active immunization of women is an appealing strategy for the prevention of GBS disease in
pregnant women and their infants during the first 3 months of infant life.
In this study 65 healthy, non-pregnant women will receive a single dose of one of two anti-streptococcal vaccinations. Both types of vaccinations are given in upper arm by injection into the muscle. To assess the vaccine effectiveness, patients have blood drawn and examined at weeks 4, 8 and 26, post-vaccination. ;
Masking: Double-Blind, Primary Purpose: Prevention
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