Bacterial Infection Clinical Trial
Official title:
Mastering Hospital Antimicrobial Resistance and Its Spread Into the Community:the Role of Family Members and Caregivers in Dissemination of MDR in Rehabilitation Centers
Detailed activity:
- Family members and caregivers of carrier residents will be screened for ESBL and MRSA.
Screening will be performed by obtaining nares and perirectal cultures. Nares cultures
will be obtained by ward staff or research personnel who are experienced in performing
this activity: a moisture swab will be applied gently to the distal part of both nares.
Perirectal cultures, will be taken by swab, who will be applied to the perirectal area,
either by staff as mentioned above, or will be given to the participants to perform by
himself (with explanation on how to perform it).
- The Family and Caregiver Screening Form will be filled out; results of screening will
be added to the forms. This data will be stored after removal of all Family members'
identifiers for further analysis.
- In order to allow follow up, a list linking between the Family members' study number
and his identifying details will be kept separately in the rehabilitation center. This
list will not be transferred elsewhere.
| Status | Not yet recruiting |
| Enrollment | 400 |
| Est. completion date | January 2014 |
| Est. primary completion date | October 2009 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - Family members or caregivers of patient hospitalized in rehabilitation center and who is known carrier of the target resistant population. - Participating member older than 18 years, who attend the patient at least once a week, will be eligible for inclusion. Exclusion Criteria: - Age 18 years or less, attending the patient less than once a week. |
Observational Model: Case-Only, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| Israel | Tasmc | Tel-aviv |
| Lead Sponsor | Collaborator |
|---|---|
| Tel-Aviv Sourasky Medical Center |
Israel,
Gottesman T, Agmon O, Shwartz O, Dan M. Household transmission of carbapenemase-producing Klebsiella pneumoniae. Emerg Infect Dis. 2008 May;14(5):859-60. doi: 10.3201/eid1405.071340. — View Citation
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Family members and caregivers carriers of patients who are carriers of resistant bacteria /Family members and caregivers of patients who are carriers of resistant bacteria | one year | No |
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