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Evaluation of the Efficiency of Treatment by BUMETANIDE on Autistic Children With a Known Ethiology — BUMAUTEP  

Autistic Disorder Clinical Trial

Official title:
Evaluation of the Efficiency of Treatment by BUMETANIDE on Autistic Children With a Known Ethiology : Multicenter and Double Blind-study With Randomized Parallel Group, Against Placebo.

Clinical Trial Summary

During a previous therapeutic trial, investigators showed that the bumetanide improved significantly autism. This trial showed that a therapeutic response was obtained in 75% of cases. These first results were reinforced by a study led with adult patients for whom the eye tracking measurements as well as the functional MRI showed a diminution of the response time and a modification (amplification) of the cerebral response during an emotions recognition test. Finally, investigators confirmed the physiological mechanism behind the action of the bumetanide in a study in two mouse models of autism.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02947880
Study type Interventional
Source University Hospital, Limoges
Contact
Status Withdrawn
Phase Phase 2
Start date December 2016
Completion date June 2020
View Details
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