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Clinical Trial Summary

Despite the significant morbidity and mortality associated with catatonia in autism, no diagnostic research has attempted to identify biomarkers for catatonia. This application will use a participant's own individual brain magnetic resonance image to target the primary motor strip with transcranial magnetic stimulation; to determine if hyper-excitability of the brain directly correlates with symptoms of catatonia and social-emotional impairment in autism. Completion of this project would result in the first study to associate hyper-excitability of the brain with catatonia and core features of autism; findings which are likely to have a significant impact on the health and well-being of autistic individuals.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06016764
Study type Interventional
Source Vanderbilt University Medical Center
Contact Joshua R Smith
Phone 6159363555
Email Joshua.R.Smith@vumc.org
Status Recruiting
Phase Phase 1
Start date August 23, 2023
Completion date August 23, 2026

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