Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Other |
Genetic characteristics |
Genome wide association study from blood sample |
The baseline |
|
Other |
Blood test |
Retained blood samples tested in immunomics, metabonomics, etc |
The baseline and 3 months |
|
Other |
Blood test |
Retained blood samples tested in immunomics, metabonomics, etc |
The baseline and 6 months |
|
Other |
Blood test |
Retained blood samples tested in immunomics, metabonomics, etc |
The baseline and 12 months |
|
Other |
Gut mircobiome |
Retained stool samples tested in metabonomics, genomics, etc |
The baseline and 1 months |
|
Other |
Gut mircobiome |
Retained stool samples tested in metabonomics, genomics, etc |
The baseline and 3 months |
|
Other |
Gut mircobiome |
Retained stool samples tested in metabonomics, genomics, etc |
The baseline and 6 months |
|
Other |
Gut mircobiome |
Retained stool samples tested in metabonomics, genomics, etc |
The baseline and 12 months |
|
Other |
Head Magnetic Resonance Imaging (Head MRI) |
Head MRI is used to detect the structure and function of the brain. |
The baseline and 3 months |
|
Other |
Head Magnetic Resonance Imaging (Head MRI) |
Head MRI is used to detect the structure and function of the brain. |
The baseline and 12 months |
|
Other |
Functional near - infrared spectroscopy(f-NIRS) |
Head fNIRs is a non-invasive, non-ionizing method for measuring and imaging the functional hemodynamic response to brain activity. It measures changes in hemoglobin (Hb) concentrations within the brain by means of the characteristic absorption spectra of Hb in the near-infrared range. |
The baseline and 3 months |
|
Other |
Functional near - infrared spectroscopy(f-NIRS) |
Head fNIRs is a non-invasive, non-ionizing method for measuring and imaging the functional hemodynamic response to brain activity. It measures changes in hemoglobin (Hb) concentrations within the brain by means of the characteristic absorption spectra of Hb in the near-infrared range. |
The baseline and 6 months |
|
Other |
Functional near - infrared spectroscopy(f-NIRS) |
Head fNIRs is a non-invasive, non-ionizing method for measuring and imaging the functional hemodynamic response to brain activity. It measures changes in hemoglobin (Hb) concentrations within the brain by means of the characteristic absorption spectra of Hb in the near-infrared range. |
The baseline and 12 months |
|
Other |
Multichannel Electroencephalography signals |
The latency and amplitude measured by electroencephalogram can reflect the connectivity between brain regions. |
The baseline and 3 months |
|
Other |
Multichannel Electroencephalography signals |
The latency and amplitude measured by electroencephalogram can reflect the connectivity between brain regions. |
The baseline and 6 months |
|
Other |
Multichannel Electroencephalography signals |
The latency and amplitude measured by electroencephalogram can reflect the connectivity between brain regions. |
The baseline and 12 months |
|
Other |
Eye movements |
Variables measured by eye movements represent cognition. |
The baseline and 3 months |
|
Other |
Eye movements |
Variables measured by eye movements represent cognition. |
The baseline and 6 months |
|
Other |
Eye movements |
Variables measured by eye movements represent cognition. |
The baseline and 12 months |
|
Other |
Behaviour assessment |
The behaviour development of participants includes intellectual/developmental quotient, syptoms severity, comorbidity, etc. |
The baseline and 6 months |
|
Other |
Behaviour assessment |
The behaviour development of participants includes intellectual/developmental quotient, syptoms severity, comorbidity, etc. |
The baseline and 12 months |
|
Primary |
Behaviour assessment |
The behaviour development of participants includes intellectual/developmental quotient, syptoms severity, comorbidity, etc. |
The baseline and 3 months |
|