Mobile-based Games for Cognitive Training in Children With Neurodevelopmental Disorders

Autism Spectrum Disorder Clinical Trial

Official title:

Mobile-based Games for Cognitive Training in Children With Neurodevelopmental Disorders

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04308915
• Other study ID #: IITK/IEC/2017-18II/2
• Status: Completed
• Phase: N/A
• Start date: September 6, 2018
• Est. completion date: October 31, 2018

Study information

• Verified date: March 2020
• Source: Indian Institute of Technology Kanpur
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with characteristic deficits in social functioning and presence of stereotypic behavior. Several research studies have examined potential deficits in cognitive skills, such as working memory, in this condition. A meta-analysis of the studies aimed at evaluating working memory (WM) in autistic population suggested deficits in visual and verbal aspects of WM. Working memory training has also been studied in other neurodevelopmental disorders such as Attention Deficit Hyperactivity Disorder (ADHD). The study includes development of mobile-based games for training WM and other cognitive skills in patients and the evaluation of such training in reducing symptoms of ASD. These games may also be useful for other neurodevelopmental disorders.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14
• Est. completion date: October 31, 2018
• Est. primary completion date: October 31, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 5 Years to 16 Years

Eligibility

Inclusion Criteria:

• Diagnosis of Autism Spectrum Disorder or another related neurodevelopmental disorder with symptoms of ASD

Exclusion Criteria:

• Inability to use smartphones/tablets

• Serious intellectual disabilities.

• Sensory impairment

Related Conditions & MeSH terms

• Autism Spectrum Disorder
• Neurodevelopmental Disorders

Intervention

Behavioral:
• Game-based cognitive training
A suite of 5 games is presented to the participants for training working memory

Locations

Country	Name	City	State
India	Indian Institute of Technology Kanpur	Kanpur	Uttar Pradesh

Sponsors (1)

Lead Sponsor	Collaborator
Indian Institute of Technology Kanpur

Country where clinical trial is conducted

India, 

References & Publications (1)

de Vries M, Prins PJ, Schmand BA, Geurts HM. Working memory and cognitive flexibility-training for children with an autism spectrum disorder: a randomized controlled trial. J Child Psychol Psychiatry. 2015 May;56(5):566-76. doi: 10.1111/jcpp.12324. Epub 2014 Sep 26. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Corsi Task Block Span	It is an indicator of working memory. The value ranges between 0 and 9. Higher values mean better outcome.	change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection)
Primary	Corsi Task Total Score	It is an indicator of working memory. The minimum value is 0, the maximum value has no limit. Higher values mean better outcome.	change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection)
Secondary	Autism Treatment Evaluation Checklist Total Score	Autism Treatment Evaluation Checklist is a measure to evaluate treatments for Autism. The total score ranges between 0 and 179. Higher values mean better outcome.	change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection)