Mindreading in Adults With Autism Spectrum Disorder

Autism Spectrum Disorder Clinical Trial

Official title:

Mindreading in Adults With Autism Spectrum Disorder

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04010409
• Other study ID #: 201809069RINA
• Status: Recruiting
• Start date: January 8, 2019
• Est. completion date: December 31, 2024

Study information

• Verified date: December 2022
• Source: National Taiwan University Hospital
• Contact: Yi Ling Chien, M.D., Ph.D.
• Phone: 886-2-2312-3456
• Email: ylchien[@]hotmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study aims to investigate the ability of reading emotions by the Eyes task in adults with ASD, and examine the gazing pattern and frontal activation during the task. We plan to recruit 50 adults with ASD and 50 typically-developing adults. Eye-tracking and frontal activation (measured by functional near-infrared spectroscopy) will be examined during the Eyes task.

Description:

Autism spectrum disorder (ASD) is a clinical syndrome characterized by mindreading deficits, or Theory of Mind deficits. The Reading the Mind in the Eyes task (abbreviated as the Eyes task) was developed to assess the mindreading deficits as a hallmark of social deficits of ASD. This study aims to investigate the ability of reading emotions by the Eyes task in adults with ASD, and examine the gazing pattern and frontal activation during the task. We plan to recruit 50 adults with ASD and 50 typically-developing adults. All the participants will complete clinical measures and the Eyes task. Eye-tracking and frontal activation (measured by functional near-infrared spectroscopy) will be examined during the Eyes task.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: December 31, 2024
• Est. primary completion date: December 31, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 50 Years

Eligibility

Inclusion Criteria:

• Adult aged between 20 and 50 years who had a diagnosis of ASD based on DSM-5.

• Had a full-scale IQ > 70 on WAIS-IV.

Exclusion Criteria:

• A history of major mental illness (e.g., bipolar affective disorder, schizophrenia) or neurological diseases.

• Visual impairment and that would preclude participation.

Related Conditions & MeSH terms

• Autism Spectrum Disorder
• Autistic Disorder
• Child Development Disorders, Pervasive

Intervention

Other:
• no intervention
no intervention

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	eye tracking indicators	eye tracking indicators	30 min