Atrioventricular Block Clinical Trial
Official title:
PReventive Effect Of Left Bundle Branch Area Pacing Versus righT vEntricular paCing on All Cause deaTh, Heart Failure Progression, and Ventricular dysSYNChrony in Patients With Substantial Ventricular Pacing (PROTECT-SYNC): Multicenter Prospective Randomized Controlled Trial
PROTECT-SYNC study is a multicenter, randomized, controlled trial. A total of 7 medical centers across Republic of Korea will enroll 450 patients during 2 years of enrollment period, and followed for 2 years of follow-up period. The purpose of this study to compare the clinical outcomes of Left Bundle Branch Area Pacing (LBBAP) compared to Right Ventricular Pacing (RVP) in bradyarrhythmia patients who require high burden of ventricular pacing (>40%).
PROTECT-SYNC study is a multicenter, randomized, controlled trial that is designed to assess whether LBBAP may reduce the risk of composite primary endpoint including all cause mortalty, HF hospitalization and/or urgent HF related visit, occurrence of pacing induced CMP, and CRT-upgrade event, compared to RVP in patients who require substantial (>40%) ventricular pacing. Patients who require pacemaker and substantial (>40%) ventricular pacing will be randomized to LBBAP or RVP group, and a total of 7 medical centers across Republic of Korea will enroll 450 patients during 2 years of enrollment period, and followed for 2 years of follow-up period. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT06023784 -
The Impact of LBBAP vs RVP on the Incidence of New-onset Atrial Fibrillation in Patients With Atrioventricular Block
|
N/A | |
Completed |
NCT01019213 -
Acute and Chronic Effect of His-pacing in Consecutive Patients With AV-block
|
Phase 4 | |
Completed |
NCT04884100 -
enHEART - Exploring Full Content of Optical Signals to Enhance Cardiac Arrhythmia Screening
|
N/A | |
Recruiting |
NCT05774262 -
Pacemaker Implantation Versus Cardioneuroablation for Functional Atrioventricular Block
|
N/A | |
Terminated |
NCT04093414 -
Left Bundle Area Versus Selective His Bundle Pacing
|
N/A | |
Withdrawn |
NCT00559143 -
Biventricular Alternative Pacing
|
Phase 4 | |
Recruiting |
NCT04730921 -
Impact of Left Bundle Branch Area Pacing vs. Right Ventricular Pacing in Atrioventricular Block (LEAP-Block)
|
N/A | |
Recruiting |
NCT05575557 -
Pulmonary Artery Pressure and Right Heart Evaluation for Patients Requiring Physiological Pacing Treatment
|
N/A | |
Completed |
NCT00187278 -
Biopace Study: Biventricular Pacing for Atrioventricular Block to Prevent Cardiac Desynchronization
|
N/A | |
Recruiting |
NCT04595487 -
LVSP vs RVP in Patients With AV Conduction Disorders
|
N/A | |
Completed |
NCT04269733 -
Risk of Pacing-induced Cardiomyopathy
|
||
Recruiting |
NCT03851315 -
Left Bundle Branch Area Pacing in AVB Patients
|
||
Completed |
NCT01922518 -
Impact of Right Ventricular Pacing Determined by Electrocardiography
|
N/A | |
Completed |
NCT02282033 -
Safety and Performance Study of the Moderato System
|
N/A | |
Recruiting |
NCT04624763 -
Protection of Cardiac Function With Left Bundle Branch Pacing in Patients With Atrioventricular Block
|
N/A | |
Completed |
NCT03231826 -
Arrhythmias in Post-Myocardial Infarction Patients
|
||
Not yet recruiting |
NCT04437901 -
COVIDAR - Arrhythmias in COVID-19
|
||
Recruiting |
NCT01717469 -
Safety and the Effects of Isolated Left Ventricular Pacing in Patients With Bradyarrhythmias
|
Phase 4 | |
Completed |
NCT02154750 -
AV Delay Optimization vs. Intrinsic Conduction in Pacemaker Patients With Long PR Intervals
|
N/A | |
Completed |
NCT02462941 -
Analysis of Adenosine on Sinus and Atrioventricular Nodal Conduction in the Pediatric Transplanted Heart
|
Phase 1 |