Atrial Fibrillation Clinical Trial
Official title:
EARLY-MYO-AF (EARLY Integrated Therapies on MYOcardial Function Improvements in Patients With Atrial Fibrillation) Registry
The purpose of this registry is to depict the myocardial function improvement in AF patients by integrated therapy and to assess the prognostic discrepancies of various intervention modalities. Information will be collected prospectively in about 5000 AF patients. Subjects will be followed for up to 3 years.
This is a prospective, single-centered, non-randomized, observational registry study of AF
patients that undergo radio-frequency catheter ablation, left atrial appendage occlusion or
surgical ablation. Information of other medication intervention and clinical outcomes are
also prospectively collected in the database. This project will establish a prospective
registry of 5000 AF patients with follow-ups of up to 3 years.
The aim of the project will be as following:
1. To investigate pathophysiological changes of both atrial and ventricular myocardial
function in AF patients.
2. To identify clinical indices (including baseline, comorbidities, medication or
operational interventions) that are associated with adverse clinical outcomes.
3. To spot potential therapeutical targets in the continuum of AF: from risk-factors
elimination to mortality and disability prevalence reduciton.
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