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Clinical Trial Summary

A randomized, open-blinded, prospective study to evaluate the timeliness and safety of direct current cardioversion (DCCV) when using methohexital when compared to the more often used propofol.


Clinical Trial Description

The investigators theorize that the use of methohexital during cardioversion will result in a shorter time to effective sedation and time to full recovery when compared to the use of propofol. This will change how sedation is approached for elective cardioversions. Primary Hypothesis: 1. The mean time to recovery from sedation during a cardioversion using methohexital for sedation will be significantly shorter than the recovery time using propofol for sedation, as evidenced by a short time from initiation of induction to a score of 2 on the Ramsay Sedation Scale. 2. The mean time to a Ramsay score of 5-6 will be significantly shorter using methohexital than the time to the same sedation level using propofol Secondary Hypothesis: 1. There will be no significant increase in adverse events associated with the use of methohexital when compared with propofol. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04187196
Study type Interventional
Source Wake Forest University Health Sciences
Contact
Status Completed
Phase Phase 4
Start date April 29, 2020
Completion date September 28, 2022

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