Atrial Fibrillation Clinical Trial
Official title:
Analysis of the Endocavitary Electrical Signal and Surface Electrocardiogram to Determine Relevant Features for an Accurate Prediction of Ablation Outcome for Patients in Persistent Atrial Fibrillation
Background :
Despite recent progress in the management of patients with Atrial Fibrillation (AF), AF
remains one of the main risk factor of stroke, heart failure and cardiovascular mortality in
the world. AF is the most common cardiac arrhythmia, and its prevalence is expected to grow
in the coming years.
Catheter ablation (CA) of AF can be successful in restoring and maintaining Sinus rhythm (SR)
in patients with paroxysmal, and persistent AF. Haissaguerre et al. have shown that AF
ablation of the heart by isolating the Pulmonary Vein is usually sufficient. However, when
ablating persistent AF patients ablating pathological regions in the atria is also required.
CA is still a challenging procedure, and reported success rate for persistent AF patients
remains relatively low (around 60%). This procedure is associated with risks inherent to any
invasive cardiac procedures.
A better identification of good responders would reduce the risks associated with ablation,
especially for patients with low odds of favorable outcome, while also increasing the success
rate of the procedure. It has been shown in the literature the long-term CA outcome can be
predicted non-invasively by atrial fibrillatory wave (f-wave) amplitudes.
Hypothesis :
We assume that a morphological analysis of the f-waves on standard twelve ECG will allow for
a better CA outcome prediction.
Objectives :
The aim of this study is to automatically analyse the morphology of the ECG signal before a
CA procedure, extract relevant features for an accurate prediction of long-term CA outcome
for patients in persistent AF.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05654272 -
Development of CIRC Technologies
|
||
| Completed |
NCT04571385 -
A Study Evaluating the Efficacy and Safety of AP30663 for Cardioversion in Participants With Atrial Fibrillation (AF)
|
Phase 2 | |
| Terminated |
NCT04115735 -
His Bundle Recording From Subclavian Vein
|
||
| Completed |
NCT05366803 -
Women's Health Initiative Silent Atrial Fibrillation Recording Study
|
N/A | |
| Completed |
NCT02864758 -
Benefit-Risk Of Arterial THrombotic prEvention With Rivaroxaban for Atrial Fibrillation in France
|
||
| Recruiting |
NCT05442203 -
Electrocardiogram-based Artificial Intelligence-assisted Detection of Heart Disease
|
N/A | |
| Completed |
NCT05599308 -
Evaluation of Blood Pressure Monitor With AFib Screening Feature
|
N/A | |
| Completed |
NCT03790917 -
Assessment of Adherence to New Oral anTicoagulants in Atrial Fibrillation patiEnts Within the Outpatient registrY
|
||
| Enrolling by invitation |
NCT05890274 -
Atrial Fibrillation (AF) and Electrocardiogram (EKG) Interpretation Project ECHO
|
N/A | |
| Recruiting |
NCT05316870 -
Construction and Effect Evaluation of Anticoagulation Management Model in Atrial Fibrillation
|
N/A | |
| Recruiting |
NCT05266144 -
Atrial Fibrillation Patients Treated With Catheter Ablation
|
||
| Not yet recruiting |
NCT06023784 -
The Impact of LBBAP vs RVP on the Incidence of New-onset Atrial Fibrillation in Patients With Atrioventricular Block
|
N/A | |
| Recruiting |
NCT05572814 -
Transform: Teaching, Technology, and Teams
|
N/A | |
| Recruiting |
NCT04092985 -
Smart Watch iECG for the Detection of Cardiac Arrhythmias
|
||
| Completed |
NCT04087122 -
Evaluate the Efficiency Impact of Conducting Active Temperature Management During Cardiac Cryoablation Procedures
|
N/A | |
| Completed |
NCT06283654 -
Relieving the Emergency Department by Using a 1-lead ECG Device for Atrial Fibrillation Patients After Pulmonary Vein Isolation
|
||
| Recruiting |
NCT05416086 -
iCLAS™ Cryoablation System Post-Market Clinical Follow-up (PMCF) Study
|
N/A | |
| Completed |
NCT05067114 -
Solutions for Atrial Fibrillation Edvocacy (SAFE)
|
||
| Completed |
NCT04546763 -
Study Watch AF Detection At Home
|
||
| Completed |
NCT03761394 -
Pulsewatch: Smartwatch Monitoring for Atrial Fibrillation After Stroke
|
N/A |