Atrial Fibrillation Clinical Trial
Official title:
Detection Rate of Atrial Fibrillation in Patients Implanted With ILRs
Implantable Loop Recorders (ILRs), are subcutaneous heart monitors, which are implanted for
different reasons including syncope (fainting), pre syncope (near fainting), palpitations
and stroke. They monitor the heart and detect abnormalities.
Atrial fibrillation (irregular heart rhythm),is a common cardiac arrhythmia associated with
a five-fold risk of stroke. Atrial Fibrillation increases the risk of stroke in patients to
a different degree according to a risk stratification score. Anticoagulation is recommended
to all high-risk patients.
Recent published studies have shown a high incidence of Atrial Fibrillation detected by ILRs
in patients with previous stroke.
It is not known whether a similar incidence of Atrial Fibrillation occurs in patients
without previous stroke. It is also not know ''how much'' Atrial Fibrillation is necessary
to increase the risk of stroke, how relevant the finding of Atrial Fibrillation is and
whether everybody with Atrial Fibrillation should have anticoagulation or whether a "bit of
Atrial Fibrillation" is actually normal in most people.
The purpose of this study is to identify and compare the rate and the burden of Atrial
Fibrillation (more or less than 30 seconds) in patients with and without previous stroke.
Medical notes and Implantable Loop Recorder records of the patients that had the devices
implanted in Addendbrooke's Hospital from March 2009 up to 1 month after the implantation of
the latest device will be inspected in order to identify whether the device had detected
Atrial Fibrillation and if so the burden of Atrial Fibrillation in the two different groups
of patients (with and without previous stroke).
The risk of stroke for each patient will be calculated. Echocardiographic (ultrasound scan
of the heart)risk factors for Atrial Fibrillation will be identified and compared between
the two groups.
This is going to be a retrospective study and we will be inspecting patients' data only.
Implantable Loop Recorders (ILRs), are subcutaneous heart monitors, which are implanted for
different reasons including syncope (fainting), pre syncope (near fainting), palpitations
and stroke. They monitor the heart and detect abnormalities.
Atrial fibrillation (irregular heart rhythm),is a common cardiac arrhythmia associated with
a five-fold risk of stroke. Atrial Fibrillation increases the risk of stroke in patients to
a different degree according to a risk stratification score. Anticoagulation is recommended
to all high-risk patients.
Recent published studies have shown a high incidence of Atrial Fibrillation detected by ILRs
in patients with previous stroke.
It is not known whether a similar incidence of Atrial Fibrillation occurs in patients
without previous stroke. It is also not know ''how much'' Atrial Fibrillation is necessary
to increase the risk of stroke, how relevant the finding of Atrial Fibrillation is and
whether everybody with Atrial Fibrillation should have anticoagulation or whether a "bit of
Atrial Fibrillation" is actually normal in most people.
The purpose of this study is to identify and compare the rate and the burden of Atrial
Fibrillation (more or less than 30 seconds) in patients with and without previous stroke.
Medical notes and Implantable Loop Recorder records of the patients that had the devices
implanted in Addendbrooke's Hospital from March 2009 up to 1 month after the implantation of
the latest device will be inspected in order to identify whether the device had detected
Atrial Fibrillation and if so the burden of Atrial Fibrillation in the two different groups
of patients (with and without previous stroke).
The risk of stroke for each patient will be calculated. Echocardiographic (ultrasound scan
of the heart)risk factors for Atrial Fibrillation will be identified and compared between
the two groups.
This is going to be a retrospective study and we will be inspecting patients' data only..
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Observational Model: Case Control, Time Perspective: Retrospective
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