Optimization of Initial Energy for Cardioversion of Atrial Fibrillation With Biphasic Shocks — OPTIMA  

Atrial Fibrillation Clinical Trial

Official title: Optimization of Initial Energy for Cardioversion of Atrial Fibrillation With Biphasic Shocks (OPTIMA Trial).

Status Recruiting

Clinical Trial Summary

Use of higher energy doses (120-150 J) may not offer additional benefits and higher success rate compared with low to moderate initial energy (100-120 J) of biphasic shock for atrial fibrillation cardioversion. In this prospective open-label randomized trial consecutive patients with AF and candidate to AF electrical cardioversion will be randomized to receive 100J or 120 J as initial dose of biphasic shock. Patients will be also randomized in each group to anterolateral or postero-anteriore placement of defibrillator electrodes.

Clinical Trial Description

Open-label randomized trial to assess the efficacy of alternative initial biphasic shocks (100 versus 120 J) for cardioversion of atrial fibrillation including alternative option for electrode placement (anterolateral or postero-anterior in each group). ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Atrial Fibrillation
• Cardioversion

• NCT number: NCT01910779
• Study type: Interventional
• Source: Maria Vittoria Hospital
• Contact: Massimo Imazio, MD
• Phone: +39011439
• Email: massimo_imazio@yahoo.it
• Status: Recruiting
• Phase: N/A
• Start date: May 2013
• Completion date: April 2014