Atrial Fibrillation Clinical Trial
Official title:
Effect of Ascorbic Acid on the Incidence of Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Verified date | May 2015 |
Source | Regional Hospital of Scranton |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Institutional Review Board |
Study type | Interventional |
The purpose of this study is to determine if vitamin C decreases the chance of developing atrial fibrillation, a type of arrhythmia or irregular heartbeat, following cardiac surgery. This irregular heartbeat is a common occurrence following cardiac surgery, and occurs in about one third of patients. It poses extra risks to people who develop it. Our hypothesis is that Vitamin C will decrease the incidence of postoperative atrial fibrillation.
Status | Withdrawn |
Enrollment | 0 |
Est. completion date | August 2015 |
Est. primary completion date | July 2015 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 50 Years and older |
Eligibility |
Inclusion Criteria: - Adults 50 years of age or older - Undergoing elective or urgent coronary artery bypass graft surgery, valve surgery, or a combination of the two Exclusion Criteria: - Prior cardiac surgery - History of atrial fibrillation - Permanent or temporary pace maker - Currently taking digoxin or Vaughan Williams Class I or III antiarrhythmic medications - Known hyperoxaluria - History of renal calculi - History of allergic or hypersensitivity reaction to ascorbic acid products - Currently taking 1 g or more of ascorbic acid supplementation daily |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
United States | Regional Hospital of Scranton | Scranton | Pennsylvania |
Lead Sponsor | Collaborator |
---|---|
Regional Hospital of Scranton |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Post-operative atrial fibrillation | Patients will be followed for the entire hospital stay, with an expected average of 5 days | No | |
Secondary | Hospital length of stay | 30 Days | No | |
Secondary | Intensive care unit length of stay | 30 Days | No | |
Secondary | Stroke | 30 Days | No | |
Secondary | Transient ischemic attack | 30 Days | No | |
Secondary | Mortality | 30 Days | No | |
Secondary | Hospital Readmission for atrial fibrillation | 30 Days | No |
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