Atrial Fibrillation Clinical Trial
Official title:
Randomised Study of the Effect of Exercise Training on Patients in Atrial Fibrillation
PURPOSE Physical exercise is beneficial for patients with ischemic heart disease and chronic
heart failure, while little is known about the effect in atrial fibrillation (AF). The
investigators studied the effect of physical exercise on cardiac output (CO), max. exercise
capacity, biomarkers and quality of life (Qol) in patients with AF in a randomised study of
physical exercise training three times weekly for twelve weeks.
HYPOTHESIS Exercise training improves cardiac output (CO), max. exercise capacity,
biomarkers and quality of life (Qol) in patients with AF.
METHODS Assessment of exercise capacity, CO, Qol, body composition, six minute walk test and
muscular strength was performed before and after 12 weeks.
Resting echocardiography was done at baseline. CO was measured using impedance cardiography
at rest and during maximal exercise testing on an ergometer bicycle. Body composition,
muscular strength and six minutes walking capacity were measured before and after the
training period. Qol was evaluated by the use of the standardized validated questionnaires
Short Form 36 (SF-36) and the Minnesota Living with Heart Failure Questionnaire (MLHF-Q).
Training consisted of aerobic exercise at 70 percent of max. capacity estimated by
Borg-scale.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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