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NCT00412438 Clinical Trial

Investigation of Genetic Risk of Atrial Fibrillation

Atrial Fibrillation Clinical Trial

Official title:
Investigation of Genetic Risk of Atrial Fibrillation

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT00412438
Other study ID # RIEM-G-1
Secondary ID
Status Recruiting
Phase N/A
First received December 15, 2006
Last updated December 15, 2006
Start date October 2006

Study information
Verified date December 2006
Source Nagoya University
Contact Kenji Yasui, MD, PhD
Phone +81-52-788-6211
Email kenji@riem.nagoya-u.ac.jp
Is FDA regulated No
Health authority Japan: Ministry of Education, Culture, Sports, Science and Technology
Study type Observational

Clinical Trial Summary

The atrial fibrillation (AF) is the most common cardiac rhythm disturbance that is responsible for substantial morbidity and mortality independent of associated heart disease or other risk factors. Even in the absence of preexisting cardiovascular disease, AF remains significantly associated with excess mortality rates. The current unsatisfactory treatment for AF comes from lack of understanding of the pathophysiology of AF. The purpose of this study is to identify gene polymorphisms that confer susceptibility to atrial fibrillation. Patients with AF（N=500） and healthy volunteer（N=1000） without AF are enrolled in this study. Patients with coronary artery disease, severe valvular heart disease, cardiomyopathy or heart failure were excluded from the study.

Recruitment information / eligibility
Status Recruiting
Enrollment 1000
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group N/A and older
Eligibility Inclusion Criteria:

- Clinical diagnosis of atrial fibirillation

Exclusion Criteria:

- coronary artery disease

- severe valvular heart disease

- cardiomyopathy

- heart failure

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
Japan Department of Bio-information Analysis, Research Institute of Enviromental Medicine, Nagoya University Nagoya Aichi

Sponsors (1)
Lead Sponsor Collaborator
Nagoya University

Country where clinical trial is conducted

Japan, 

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