Cardioversion vs. Catheter Ablation for Persistent Atrial Fibrillation

Status Recruiting

Clinical Trial Summary

The aim of this randomized study is to evaluate the efficacy of two different approaches for conversion of persistent atrial fibrillation, the non-invasive one (external electrical cardioversion) and the invasive one (catheter ablation).

Clinical Trial Description

This randomized study compares two treatment strategies in patients with persistent atrial fibrillation: Cardioversion vs. catheter ablation. Cardioversion is a low risk standard treatment option for patients with persistent atrial fibrillation. However, mid- and long term efficacy (regarding the maintenance of sinus rhythm) is low. Catheter ablation is an invasive treatment which has been reported to result in up to 60-70% of patients in stable sinus rhythm. However, it is a potentially dangerous invasive procedure with potentially fatal complications.

Comparison: External cardioversion vs. catheter ablation ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Atrial Fibrillation

Clinical Trial Details

NCT number	NCT00196209
Study type	Interventional
Source	Deutsches Herzzentrum Muenchen
Contact	Heidi L Estner, MD
Phone	0049 89 1218 2020
Email	estner@dhm.mhn.de
Status	Recruiting
Phase	Phase 4
Start date	August 2005
Completion date	December 2009

View Details

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