Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03356301
Other study ID # 2017-A01872-51
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date December 1, 2017
Est. completion date March 8, 2019

Study information

Verified date January 2019
Source Central Hospital, Nancy, France
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Regular sustained physical activity creates a cardiac remodelling : it is athlete's heart. In our preliminary work published in 2016, the investigators demonstrated in a small population of triathletes that there is also a vascular remodelling named athlete's artery. Moreover, the investigators know that left ventricle and aorta behave together like a couple. So they want to study by Cardiovascular Magnetic Resonance Imaging the impact of triathlon on the cardiac AND aortic remodelling.


Recruitment information / eligibility

Status Completed
Enrollment 63
Est. completion date March 8, 2019
Est. primary completion date March 8, 2019
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Male
Age group 18 Years to 39 Years
Eligibility Inclusion Criteria:

- to be enrolled in a social security plan.

- to have a BMI between 18,5 and 25 kg/m²

- to have received full information on the organization of the research and having signed its informed consent

- to have carried out a clinical screening adapted to the research

*** Triathlete group:

- to have a minimum performance level: between 2h and 2h45 on an M triathlon during the past year (provide proof),

- to participate in 2018 in a long distance triathlon, i. e. at least distance L

- to have a defined training volume: less than 8 hours per week during the winter months and between 10 and 15 hours per week in preparation of the objective

***Control group:

- to have no more than 150 minutes of moderate physical activity per week (footing, brisk walking, cycling, etc.).

Exclusion Criteria:

- Persons referred to in Articles L. 1121-5 to L. 1121-8 and L1122-2 of the Public Health Code

- Cardiovascular history including Ii.e. known heart rhythm disorders

- Chronic disease: diabetes, high blood pressure...

- Long-term drug therapies that may modify cardiovascular remodeling such as Conversion Enzyme Inhibitor, Angiotensin II Receptor Antagonist,

- Active smoking, even if occasional

- Contraindication to MRI

Study Design


Related Conditions & MeSH terms


Intervention

Device:
Cardiac MRI
Non injected cardiac MRI exam
Applanation tonometry
Applanation tonometry and ECG

Locations

Country Name City State
France Central Hospital Nancy

Sponsors (1)

Lead Sponsor Collaborator
Central Hospital, Nancy, France

Country where clinical trial is conducted

France, 

References & Publications (1)

Dupont AC, Poussel M, Hossu G, Marie PY, Chenuel B, Felblinger J, Mandry D. Aortic compliance variation in long male distance triathletes: A new insight into the athlete's artery? J Sci Med Sport. 2017 Jun;20(6):539-542. doi: 10.1016/j.jsams.2016.10.009. Epub 2016 Oct 29. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Aortic compliance in triathletes in mm2/mmHG aortic compliance = pulsed pressure-to-absolute variation of aortic surface ratio at baseline, at the fitness peak (6 to 10 months later) and at recovery (3 to 6 months after the fitness peak)
See also
  Status Clinical Trial Phase
Recruiting NCT06072469 - Comparison of Shoulder Range of Motion and Isometric Strength Before and After a Single Badminton Match in Young Elite Badminton Players of Rawalpindi.
Recruiting NCT06017180 - Effects of Myofascial Release Technique on Mobility, Sensorimotor Function and Performance in Volleyball Players N/A
Recruiting NCT06194110 - Comparing Stationary and Mobile Ergospirometry
Active, not recruiting NCT06224335 - Measurement of Intravaginal and Intra-abdominal Pressure and Pad Test During Sports Activities (SPORTVAGPRES)
Not yet recruiting NCT05832710 - The Project NRG - Part 1: Validation of Methods for Estimating Resting Energy Expenditure
Recruiting NCT06200493 - Effects of Maximum Strength and Acceleration Ability on Performance and Training in Wheelchair Sports
Not yet recruiting NCT05936840 - Quantum Menstrual Health Monitoring Study
Completed NCT06196268 - Core Strengthening vs Pilates Exercises on Posture, Body Awareness and Fatigue Among Female Athletes N/A
Recruiting NCT06377306 - Identifying Periods of High Training Load Considering the Menstrual Cycle Phases in Elite and Non-elite Female Athletes
Not yet recruiting NCT04628403 - Effects of Clinical Interventions for the Management of Late Start N/A
Completed NCT04107545 - Metabolic, Functional and Nutritional Responses to Weight Cycling in Athletes: The WAVE Study N/A
Completed NCT06134778 - Effect of Inspiratory Muscle Training on Cardiopulmonary Capacity in Wheelchair Rugby Athletes N/A
Completed NCT05307159 - Effect of a Bean Protein-added Supplement on Body Composition in High-performance Adolescent Athletes N/A
Completed NCT03524989 - The Effect of Hyperbaric Oxygen Therapy on Aerobic and Anaerobic Physical Fitness N/A
Completed NCT05143879 - Long-Term Effect of Combined Citrulline and Nitrate-Rich Beetroot Extract Supplementation N/A
Completed NCT05883046 - The Acute Effects of Combined Caffeine and Sodium Bicarbonate Consumption on Isometric Mid-thigh Pull N/A
Completed NCT03862508 - Plyometric Work Together With the Use of Ballast Weight in Lower Limbs in the Improvement of Performance in Jumpers N/A
Completed NCT05347303 - Orthopedic Manual Therapy vs Foam Roller on Flexibility, Joint Range of Motion, rm and Vertical Jump N/A
Completed NCT04206579 - Oral Dextrose Formula in Performance of Soccer Athlete N/A
Completed NCT03886376 - Systematic Massage on Swimming Athletes Performance N/A