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NCT00960401 Clinical Trial

A Study of Atherosclerosis in Patients After Radiation Treatment for Breast Cancer

Atherosclerosis Clinical Trial

— ABCART  

Official title:
Pilot Study "A Study of Atherosclerosis in Patients After Radiation Treatment for Breast Cancer"

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00960401
Other study ID # 05018
Secondary ID
Status Completed
Phase
First received
Last updated
Start date August 2005
Est. completion date January 2014

Study information
Verified date February 2023
Source Winthrop University Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to compare plaque burden in the coronary and carotid arteries 5 years after adjuvant radiotherapy in women with right sided breast cancer vs left sided breast cancer.

Description:

This study reviews case series of patients with a history of breast cancer treated with radiotherapy for at least five years. The study measures atherosclerosis by using coronary and carotid artery calcium scoring.

Recruitment information / eligibility
Status Completed
Enrollment 20
Est. completion date January 2014
Est. primary completion date May 2007
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 18 Years to 60 Years
Eligibility Inclusion Criteria: - women dx with ductal carcinoma in situ or breast cancer, stage 0 to stage IIIc, who received conservative surgery and radiotherapy at least 5 years ago - less than or equal to age 60 Exclusion Criteria: - hx of coronary disease prior to tx of ductal carcinoma in situ or breast cancer

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States Winthrop University Hospital Mineola New York

Sponsors (1)
Lead Sponsor Collaborator
Winthrop University Hospital

Country where clinical trial is conducted

United States, 

References & Publications (1)

Chang M, Suh J, Kirtani V, Dobrescu A, Haas J, Zeldis S, Shayani S, Hindenburg AA. Coronary Calcium Scanning in Patients after Adjuvant Radiation for Early Breast Cancer and Ductal Carcinoma In situ. Front Oncol. 2013 Sep 25;3:253. doi: 10.3389/fonc.2013.00253. eCollection 2013. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Number of Participants Analyzed for Coronary Calcium Burden by AGS Number of participants who received a coronary calcium scan. Year 5 Post-Initiation of Radiotherapy
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