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Effect of Atorvastatin and Lifestyle Intervention on Progression of Pre-Clinical Atherosclerosis — EALIPPCA  

Atherosclerosis Clinical Trial

Official title:
Effect of Atorvastatin and Lifestyle Intervention on Progression of Carotid Intima-Media Thickness in Chinese People Without Manifest Atherosclerotic Disease

Clinical Trial Summary

The purpose of this study is to determine whether atorvastatin, aggressive lifestyle intervention, and their interaction are effective in delaying the progress of pre-clinical atherosclerosis.

Clinical Trial Description

Primary prevention of atherosclerotic disease remains a big challenge. Currently, it is not clear how to treat those subjects with evidence of pre-clinical atherosclerosis but without obvious conventional risk factors. This randomized, placebo controlled, double blind study is to evaluate the effect of Atorvastatin 10 mg daily, therapeutic lifestyle change, and their combination, on the progression of CIMT in those with higher baseline CIMT value but are not belong to 'high risk' category, according to the conventional risk factors. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Factorial Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00723320
Study type Interventional
Source Ministry of Science and Technology of the People´s Republic of China
Contact Jianping Li
Phone 86-10-66551122
Status Recruiting
Phase N/A
Start date February 2008
Completion date December 2010
View Details
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