Clinical Trials Logo
  1. Home
  2. Asymptomatic Bacteriuria
  3. NCT02373085

Prospective Comparative Study About Treatment of Asymptomatic Bacteriuria in Kidney Transplant Recipients.

Asymptomatic Bacteriuria Clinical Trial

Official title:
Effect of Systematic Search and Antimicrobial Treatment of Asymptomatic Bacteriuria in Kidney Transplant Recipients in the Incidence of Acute Pyelonephritis: a Pragmatic Prospective Randomized Controlled Study.

Clinical Trial Summary

Antimicrobial treatment of asymptomatic bacteriuria (AB) in kidney transplant recipients (KTR) is controversial. The investigators performed a comparative, parallel-group, randomized, open-label study to assess, in a real clinical setting, the feasibility of and benefit derived from systematic search and antimicrobial treatment of all episodes of AB.

Clinical Trial Description

All patients undergoing KT between January 2011 and December 2013 in a tertiary-care center with an active transplantation program were systematically searched for AB within the first 2 years after transplantation on a regular basis. During the first 2 months after transplantation all episodes of AB were treated. Thereafter, patients were assigned, according to a computer-generated randomization sequence, to group A (systematic antimicrobial treatment of all episodes of AB) or group B (no treatment). Treatment was chosen according to the results of the urine culture. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02373085
Study type Interventional
Source López-Medrano, Francisco, M.D.
Contact
Status Completed
Phase N/A
Start date January 2011
Completion date January 2015
View Details
See also
  Status Clinical Trial Phase
Completed NCT03235947 - Perioperative Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients Phase 4
Completed NCT04289753 - Behavioral Economics Applications to Geriatrics Leveraging EHRs R33 Trial N/A
Recruiting NCT05055856 - Asymptomatic Bacteriuria, Hyponatremia and Geri-atric Syndrome N/A
Completed NCT00781339 - Safety and Efficacy Study of NVC-422 on Bacteriuria in Catheterized Patients Phase 2
Completed NCT03554603 - Modified Reporting of Positive Urine Cultures Collected From Long Term Care N/A
Completed NCT04055675 - Urinalysis Results in Healthy Individuals
Completed NCT01052545 - Asymptomatic Bacteriuria Guideline Implementation Study N/A
Recruiting NCT04152369 - "Peri-operative Antimicrobial Prophylaxis in Patients With Asymptomatic Bacteriuria of Enterobacteriacae ESBL+ Origin" N/A
Recruiting NCT03269604 - Effectiveness of Three Times of Starting Antibiotic Prophylaxis in Patients With Asymptomatic Bacteriuria. N/A
Recruiting NCT01771432 - Antibiotic Treatment Versus no Therapy in Kidney Transplant Recipients With Asymptomatic Bacteriuria N/A
Completed NCT03704389 - Behavioral Economics Applications to Geriatrics Leveraging EHRs N/A
Completed NCT04333602 - Asymptomatic Bacteriuria in Early Kidney Transplantation Follow up N/A
Completed NCT03445312 - Safety and Effectiveness of a Laboratory Intervention to Effectively NOT Treat Asymptomatic Bacteriuria
Completed NCT00506025 - Effectiveness of Cranberry Ingestion on Bacterial Adhesion: An Adjunct Study N/A
Recruiting NCT05554081 - Effect of Standardization of Urine Collection Using PEEZY Device as Compared to Clean Peezy for DAB Phase 3
Completed NCT01871753 - The Bacteriuria in Renal Transplantation (BiRT) Study: A Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria Phase 4
Completed NCT01820897 - Efficacy of Fosfomycin-Trometamol in Urinary Tract Infection Prophylaxis After Kidney Transplantation Phase 4