Contoura vs Wavefront Optimized Ablation

Status Not yet recruiting

Clinical Trial Summary

To evaluate the efficacy, safety and accuracy of Contoura topography-guided LASIK & PRK in comparison to Wavefront optimized LASIK & PRK in virgin eyes with astigmatism.

Clinical Trial Description

In Upper Egypt, The second principal cause of blindness was uncorrected refractive errors accounting for 16% of sample population. It was reported that astigmatism (defined as cylinder power > 0.5 D) was the most common refractive errors in children and adults followed by hyperopia and myopia. Laser vision correction has been established over the last 2 decades as a safe and effective intervention to treat refractive errors, being one of the main techniques practiced globally. However, many subjects after LASIK had uncorrected distance visual acuity (UDVA) greater than 1.0, they complain about poor night vision, glare, and double vision. As studies have shown that every 1° deviation of the astigmatic axis could result in loss of correction of 3.3%. Even residual astigmatism less than 0.50D could have an actual impact on visual quality. Excimer laser ablation used in the correction of refracted errors especially astigmatism may reduce quality of vision, and that is attributed to the induced optical aberrations. The most prevalent of these optical aberrations is the spherical aberration. Among multiple sophisticated profiles that developed to optimize visual outcomes, wavefront optimized profile which compensate for corneal curvature to reduce spherical aberration. The topographic guided profiles which consider the shape of the anterior corneal surface. Contoura topography guided ablation corrects astigmatic power and axis to create a more uniform, aberration-free cornea. Treating astigmatism can be challenging as the conventional patterns of Excimer laser treatment of astigmatism is known to be less predictable than that of spherical refractive errors. ;

Study Design

Related Conditions & MeSH terms

Astigmatism

Clinical Trial Details

NCT number	NCT05829980
Study type	Observational
Source	Assiut University
Contact	Mohamed S. Saad Abdallah, Professor
Phone	01001825024
Email	mohsayedsaad@aun.edu.eg
Status	Not yet recruiting
Phase
Start date	June 2023
Completion date	April 2025

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT04778501` - PMCF Study on Monofocal Toric IOL (PODEYE TORIC) in Asia	N/A
Completed	`NCT04536571` - Vision Stability and Preference for Soft Toric vs. Soft Spherical Contact Lenses	N/A
Completed	`NCT04613882` - Quantification of the Visual Benefits of Soft Toric Contact Lenses Compared to Soft Spherical Contact Lenses	N/A
Completed	`NCT05039112` - Clinical Comparison of 2 Daily Disposable Toric Soft Contact Lenses	N/A
Recruiting	`NCT05611294` - Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction	N/A
Completed	`NCT05633082` - A Clinical Performance of Two Soft Toric Contact Lenses	N/A
Not yet recruiting	`NCT05561296` - Astigmatism Management With Iris-registration Guided Corneal Relaxing Incisions or Toric IOLs During Cataract Surgery	N/A
Not yet recruiting	`NCT05506553` - Comparison of Aspheric Toric Intraocular Lenses for Micro-monovision	N/A
Completed	`NCT02847169` - Clinical Performance of Toric Hydrogel Contact Lenses Following One Week of Daily Wear	N/A
Recruiting	`NCT02618018` - Clinical Evaluation of Efficacy and Stability of AT TORBI 709M 4-haptic Toric IOL in Cataract Surgery	N/A
Completed	`NCT02423109` - Bilateral Dispensing Study of Fanfilcon A Toric Versus Enfilcon A Toric Lenses	N/A
Completed	`NCT02550353` - Changes Between Lenticule Extraction and Femtosecond Laser-assisted Laser in Situ Keratomileusis	N/A
Completed	`NCT02555098` - A Bilateral Dispensing Clinical Trial of an Sapphire Lens Against Senofilcon A Toric for Astigmatism Lens	N/A
Completed	`NCT02551796` - Early Changes Among FLEx, LASIK and FS-LASIK	N/A
Completed	`NCT02248766` - Clinical Performance of Habitual Wearers of Avaira Toric When Refitted With Clariti Toric Lenses	N/A
Completed	`NCT01965288` - Clinical Performance of Biofinity Toric Versus Air Optix for Astigmatism	N/A
Completed	`NCT01857102` - Toric Eye Strain and Stability Study	N/A
Withdrawn	`NCT01680354` - Surgical Correction of Astigmatism	N/A
Completed	`NCT02624791` - Evaluating and Improving Functional Driving Vision of Patients With Astigmatism	N/A
Completed	`NCT01207466` - Evaluation of Two Daily Disposable Contact Lenses for Wearers With Astigmatism	N/A