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Clinical Trial Summary

This study will assess the efficacy and safety of dexpramipexole as an adjunctive oral therapy in participants with inadequately controlled asthma with an eosinophilic phenotype and a history of asthma exacerbations.


Clinical Trial Description

This is a multicenter, randomized, double-blind, placebo controlled, parallel group study designed to evaluate the efficacy and safety of dexpramipexole in adults and adolescents with severe, inadequately controlled asthma with eosinophilic phenotype on medium to high-dose inhaled corticosteroids (ICS )and at least one additional asthma controller medication with or without oral corticosteroids (OCS). Approximately 1400 participants will be randomized globally. Participants will receive dexpramipexole, or placebo, administered orally, over a 52-week treatment period. The study also includes a post-treatment follow-up period of 4 weeks. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05763121
Study type Interventional
Source Areteia Therapeutics
Contact EXHALE Recruiting
Phone 888-584-9281
Email clinicaltrials@areteiatx.com
Status Recruiting
Phase Phase 3
Start date January 30, 2023
Completion date July 2026

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