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Asthma L-Citrulline Pilot Study — ALPS  

Asthma Clinical Trial

Official title:
Asthma L-Citrulline Pilot Study

Clinical Trial Summary

This study will evaluate whether treatment with L-citrulline, which is an amino acid found in some foods, can increase levels of L-arginine and thereby restore the concentration of nitric oxide (NO) in the airways.

Clinical Trial Description

Research has shown that some obese asthmatics have a metabolic imbalance in which L-arginine levels are reduced. L-arginine is an amino acid that is used to make NO, a gas that is normally made in the bronchi and ensures that the lungs function properly. In this pilot study subjects with asthma that have an increased body mass index compatible with being obese, will be invited to participate in a short open-label treatment with 15g/day of L-citrulline for two weeks. Study participants will be asked to do lung function testing and donate blood before and after taking the supplement. L-citrulline is safe and well tolerated and has been used at much higher doses without significant side effects. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02943161
Study type Interventional
Source University of Colorado, Denver
Contact
Status Completed
Phase N/A
Start date April 5, 2017
Completion date March 31, 2019
View Details
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