Asthma Clinical Trial
Official title:
The Comparison of Electronic Auscultation Coupled With Computer Aided Lung Sound Analysis (CALSA) and Functional Respiratory Imaging (FRI) and Repeatability of FRI Biomarkers in Healthy Subjects and Asthma Patients
CALSA will be compared with FRI and the repeatability of the FRI parameters will be tested in a group of healthy volunteers and asthma patients.
his is a study with no investigational product. CALSA will be compared with FRI and the
repeatability of the FRI parameters will be tested in a group of healthy volunteers and
asthma patients.
Electronic auscultation of respiratory sounds will be performed, lung function tests (at
maximal dilatation) will be executed and computed tomography (CT) scans of the thorax will
be taken. The scans will be taken at two different breathing levels, more specifically at
total lung capacity (TLC) and functional residual capacity (FRC) level. The scans will be
taken while the patient/ volunteer lies down on the movable table of the CT-scan. After the
scan is taken it will be asked to the patient/ volunteer to sit upright on the scanning
table and to lie down again. When the patient/ volunteer lies down a second CT-scan (TLC and
FRC) will be taken.
The objective of this study is to compare CALSA with FRI and to assess the repeatability of
FRI biomarkers
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Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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