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Steroids In Eosinophil Negative Asthma — SIENA  

Asthma Clinical Trial

Official title:
Steroids In Eosinophil Negative Asthma

Clinical Trial Summary

Because approximately half of all mild-moderately-severe asthma is persistently non-eosinophilic, it is important to determine prospectively if patients who are persistently non-eosinophilic differ in their benefit from inhaled corticosteroid treatment compared to patients who are not persistently non-eosinophilic.

Clinical Trial Description

SIENA is a 42-week randomized, stratified, 3-period double-blind placebo-controlled crossover study of patients with symptomatic mild-to-moderate asthma, not already taking an inhaled corticosteroid, in whom the effect of "medium-dose" inhaled corticosteroid (ICS) will be compared with the effect of placebo and with a long-acting muscarinic antagonist (LMA). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02066298
Study type Interventional
Source Milton S. Hershey Medical Center
Contact
Status Completed
Phase Phase 3
Start date July 2014
Completion date May 2018
View Details
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