Asthma Clinical Trial
Official title:
Characteristics of Symptomatic Asthma Remissions
This study aims at determining the patterns of asthma remission, the prevalence of these
different patterns, the various factors associated with such remissions and possible
recurrences of asthma, in order to determine the mechanisms involved in these processes.
The investigators therefore want to document these specificities in subjects in complete
remission of their asthma, and those in only symptomatic remission of their asthma, in
comparison with mildly symptomatic asthmatic subjects and healthy controls.
Primary Outcome Measures :
- Airway inflammation (% induced sputum eosinophils)
Secondary Outcome Measures:
- Perception of induced respiratory symptoms
- Airway response to methacholine and AMP, and perception scores
- Diurnal variation in Peak Expiratory Flows
- Profile of regulatory T cells in the peripheral blood
- Changes in these parameters over time (baseline, 6 months, 1 and 2 years)
;
Observational Model: Case Control, Time Perspective: Prospective
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