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NCT00188487 Clinical Trial

Magnetic Resonance (MR) in Asthmatic Patients

Asthma Clinical Trial

Official title:
MR Perfusion Imaging in Asthmatic Patients

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT00188487
Other study ID # 05-0174
Secondary ID
Status Terminated
Phase Phase 1
First received
Last updated
Start date September 2005
Est. completion date December 2005

Study information
Verified date June 2024
Source University Health Network, Toronto
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.

Description:

A cohort of 70 Asthmatic Patients and 10 controls, both sets of subjects have HRCT, MRI/A of the Thorax, and Pulmonary Function Tests to correlate the degree of pulmonary dysfunction with findings on imaging tests.

Recruitment information / eligibility
Status Terminated
Enrollment 80
Est. completion date December 2005
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 16 Years and older
Eligibility Inclusion Criteria: - All asthmatic patients are eligible. Exclusion Criteria: - Patients in whom MRI is contraindicated

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• magnetic resonance imaging (MRI) of the thorax

Locations
Country Name City State
Canada Toronto General Hospital Toronto Ontario

Sponsors (1)
Lead Sponsor Collaborator
University Health Network, Toronto

Country where clinical trial is conducted

Canada, 

Outcome
Type Measure Description Time frame Safety issue
Primary The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests
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