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NCT00043992 Clinical Trial

Outdoor Allergen Exposure, Sensitivity, and Acute Asthma

Asthma Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00043992
Other study ID # 9744-CP-001
Secondary ID
Status Completed
Phase N/A
First received August 16, 2002
Last updated September 1, 2006
Start date July 2001

Study information
Verified date September 2006
Source National Institute of Environmental Health Sciences (NIEHS)
Contact n/a
Is FDA regulated No
Health authority United States: Federal Government
Study type Observational

Clinical Trial Summary

To examine the role of outdoor pollen grains and fungal spores in the exacerbation of asthma and to produce forecasting models to predict days of high concentration.

Description:

Asthma is a growing problem, and outdoor allergens play a role in exacerbation of many cases. A clearer understanding of this role and its magnitude, and a means of controlling the effects of outdoor allergen exposures is needed. We propose Poisson time-series and conditional panel studies to test these hypotheses: 1) The incidence of acute asthma attacks, as measured by urgent care inhalation treatments and hospitalizations for asthma, has a dose-dependent relationship with exposure to specific outdoor allergens; 2) Specific sensitization to outdoor allergens is a risk factor for having an acute attack; and 3) Exposure conditions that lead to acute asthma attacks can be forecast, creating an opportunity to reduce asthma morbidity and mortality ny targeting pretreatment and/or exposure controls.

Recruitment information / eligibility
Status Completed
Enrollment 1000
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 15 Years to 50 Years
Eligibility Must be a member of the Fallon HMO and be treated for acute asthma exacerbation.

Study Design

Observational Model: Defined Population, Time Perspective: Longitudinal

Related Conditions & MeSH terms

Locations
Country Name City State
United States Fallon Clinic and Fallon Community Health Plan Worcester Massachusetts

Sponsors (1)
Lead Sponsor Collaborator
National Institute of Environmental Health Sciences (NIEHS)

Country where clinical trial is conducted

United States, 

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