Asthma Clinical Trial
Official title:
Characteristics of the Eosinophilic Asthma Phenotype: an Observational Study in Patients From a Tertiary Care Center With Various Asthma Severities: The Quebec Heart and Lung Institute-Laval University Retrospective Asthma Database Analysis
In asthma, the type and importance of the inflammatory response in the airways has allows
identification of different phenotypes. Of these, one of the most common is eosinophilic
asthma, based on induced sputum differential cell count. Patients with severe asthma and an
eosinophilic asthma phenotype have different pathophysiological characteristics than those
seen in patients with with mild asthma. However, few studies have compared patients with
eosinophilic phenotype according to the severity of asthma. In addition, the stability of the
phenotype based on the sputum results has been criticized.
This study aims to describe the characteristics of patients with eosinophilic asthma
phenotype according to the severity of asthma and determine the stability of the phenotype.
Characteristics of asthmatic subjects with sputum eosinophilia will be compared according to asthma severity. ;
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