Asthenozoospermia Clinical Trial
Official title:
Male Infertility and Complementary Treatment
Verified date | March 2018 |
Source | Gonabad University of Medical Sciences |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The present Pocock clinical trial study was conducted In the city of Mashhad in Iran between 2015 and 2016. The study inclusion criteria were men with low fertility of sperm motility<25% and total motility <50% (asthenozoospermia), no history of endocrine diseases, no diabetes men, no hormonal problems in their wives, and a healthy salpingography in their wives. The study subjects were voluntarily assigned to royal gel and IUI groups. In royal gel group, 5 grams of royal gel was used after menstruation and every other night before and after intercourse. IUI group received 75 units of FSH from the second day of the cycle. Then vaginal ultrasound was performed from the sixth day of menstrual cycle to determine the right size of follicle. 10000 units of HCG was administered when follicle diameter reached 16mm, and the study subject was prepared for IUI 32-36 hours later. Each subject alternately swapped groups following fertility failure.
Status | Completed |
Enrollment | 54 |
Est. completion date | December 10, 2017 |
Est. primary completion date | September 20, 2017 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Male-factor infertility (defined as total sperm motility<40% and sperm motility<20%) - Normal hormonal profile in women - Normal hysterosalpingography report - Regular sexual relationships Exclusion Criteria: - Ovulation dysfunction - History of sexually transmitted diseases in women and men - Hormonal disorders in men and women |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Gonabad University of Medical Sciences | Mashhad University of Medical Sciences |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Occurrence of pregnancy | Occurrence of pregnancy be detected by B-HCG test | Three months after intervention | |
Secondary | confirmation of pregnancy | Abdominal sonography to approve pregnancy and visit embryo sac. | Three months after intervention |
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