The Effect of Oral Zinc Supplementation on Thiol Oxido-reductive Index

Status Completed

Clinical Trial Summary

Although several studies have considered the relationship between infertility and semen thiol compounds levels, no study on the effects of asthenospermia treatments such as oral zinc supplementation on thiol related enzymes activity which are important in fertility of the individual has been reported.

Clinical Trial Description

The present study was conducted to study the effect of zinc supplementation on the quantitative and qualitative characteristics of semen along with reduced thiol, oxidized thiol and thiol related enzymes in the seminal plasma of asthenospermic patients. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Asthenozoospermia

Clinical Trial Details

NCT number	NCT02985905
Study type	Interventional
Source	Babylon University
Contact
Status	Completed
Phase	Phase 2
Start date	July 2011
Completion date	July 2012

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05506722` - Using of Testes Shocker in Improving the Spermatogenesis and Sperms Activity	N/A
Completed	`NCT04291495` - Evaluation of the Effects of Semen Incubation With ANDROSITOL®DGN on Sperm Motility and Mitochondrial Membrane Potential	N/A
Recruiting	`NCT05826782` - Effect of Antioxidant Food Supplement on Sperm Proteomic Structure and Semen Parameters	N/A
Completed	`NCT01954498` - Effect of Walnuts on Sperm Parameters and Male Fertility	N/A
Not yet recruiting	`NCT05792813` - Efficacy and Safety of Linggui Yangyuan Paste in Patients With Male Infertility	Early Phase 1
Recruiting	`NCT01856361` - Ramipril for the Treatment of Oligospermia	N/A
Completed	`NCT01612403` - Study the Effect of Oral Zinc Supplementation on High Molecular Weight Zinc Binding Protein in Semen	N/A
Completed	`NCT01684059` - Study the Effect of Oral Zinc Supplementation on Enzymes of Nitric Oxide Pathway	N/A
Completed	`NCT02217189` - Study of the Effect of Oral Zinc Supplementation on Superoxide Radical Scavengers	Phase 2
Recruiting	`NCT03183999` - Effect of Fermented Ginseng (GINST) on Sperm Motility	N/A
Completed	`NCT03463005` - The Effect of Royal Vaginal Gel Compared to IUI Technique on Fertility Rate of Women With Low-fertility Husbands	N/A
Recruiting	`NCT05628987` - The Association of Gut Microbiota and Spermatogenic Dysfunction
Completed	`NCT01846325` - The Effects of Administration of Combined Docosahexaenoic Acid and Vitamin E Supplements on Spermatogram and Seminal Plasma Oxidative Stress in Infertile Men With Asthenozoospermia	Phase 2/Phase 3
Completed	`NCT01828710` - Myo-inositol on Human Semen Parameters	N/A
Recruiting	`NCT05328999` - Fertility and the Microbiome
Not yet recruiting	`NCT05436080` - Epididymal U.S Findings in Asthenozoospermic &Correlation With L.Carnitine Level