Arthroscopic Knee Surgery Clinical Trial
Official title:
A Pilot Study to Determine the Efficacy of Intravenous Ibuprofen for Pain Control Following Arthroscopic Knee Surgery
The intent of this study is to assess the analgesic efficacy of IV ibuprofen when administered at induction of anesthesia. Results from this pilot study will be used to design and determine the appropriate statistical power for a larger, multi-center randomized study.
Non-steroidal anti-inflammatory drugs(NSAIDs) are an effective adjunct to opioid analgesia
for moderate-severe pain, with improvement in the quality of pain relief and consistent
evidence of opioid dose sparing. NSAIDs alone could provide effective analgesia post-surgery
when mild-moderate pain is expected. There is also evidence that the use of NSAIDs, by
avoiding or decreasing the need for opioids, can lead to a reduction in the incidence of
adverse events which are commonly attributed to, or exacerbated by, opioids.
The intent of this study is to assess the analgesic efficacy of IV ibuprofen when
administered at induction of anesthesia. Results from this pilot study will be used to
design and determine the appropriate statistical power for a larger, multi-center randomized
study.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02001662 -
Adductor Canal Block and Arthroscopic Knee Surgery, High Pain Responders
|
Phase 4 | |
| Completed |
NCT04759742 -
The Optimal Dosage of Ropivacaine for Arthroscopic Knee Surgery
|
Early Phase 1 | |
| Recruiting |
NCT06382896 -
Effect of Oliceridine on Rebound Pain
|
||
| Completed |
NCT03564886 -
Hyperosmolar Saline Irrigation Fluid in Arthroscopic Knee Surgery
|
Phase 4 | |
| Completed |
NCT02089932 -
Dexmedetomidine in Different Dose Levels as Adjuvant to Bupivacaine-induced Ultrasound-guided Femoral Nerve Block.
|
Phase 4 | |
| Completed |
NCT01701102 -
Study to Find Optimal Dose of Local Spinal Anesthetic (Mepivacaine) Combined With Narcotic (Fentanyl) For Knee Surgery
|
N/A | |
| Completed |
NCT04322760 -
Lidocaine 5% Patch Supplementation to Intra-articular Bupivacaine Dexmedetomidine After Arthroscopic Knee Surgery
|
N/A | |
| Not yet recruiting |
NCT02742376 -
Comparison of Gait Parameters Between Floor and Sponge Surfaces and Special Shoes
|
N/A |