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Arthritis, Rheumatoid clinical trials

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NCT ID: NCT02638948 Completed - Clinical trials for Rheumatoid Arthritis

Efficacy and Safety Study of BMS-986142 in Patients With Moderate to Severe Rheumatoid Arthritis

Start date: February 16, 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether the study drug, BMS-986142, is safe and effective in treating moderate to severe rheumatoid arthritis in subjects with an inadequate response to methotrexate or methotrexate and up to 2 tumour necrosis factor (TNF) Inhibitors. Patients who qualify will be randomized to either one of 3 doses of BMS-986142 or placebo in 1:1:1 randomization for 12 weeks. Disease activity and safety will be assessed over the course of the study.

NCT ID: NCT02638259 Completed - Clinical trials for Rheumatoid Arthritis

Comparative Efficacy and Safety Study of GP2015 and Enbrel® in Patients With Rheumatoid Arthritis

EQUIRA
Start date: February 21, 2015
Phase: Phase 3
Study type: Interventional

Demonstrate equivalent efficacy of GP2015 and EU-authorized Enbrel in patients with moderate to severe, active (RA) who had an inadequate response to disease modifying anti-rheumatic drugs (DMARD) including methotrexate (MTX).

NCT ID: NCT02636907 Completed - Clinical trials for Arthritis, Rheumatoid

Assessment of the Handling Experience With the BI 695501 Autoinjector in Patients With Rheumatoid Arthritis Followed by an Extension Phase Using BI 695501 Prefilled Syringe

Start date: January 6, 2016
Phase: Phase 2
Study type: Interventional

This is an open-label, phase II study of BI 695501 to assess handling experience of patients with Rheumatoid Arthritis using an autoinjector. The extension phase is to provide patients with additional exposure to BI 695501 and to enhance the safety database for this compound.

NCT ID: NCT02636829 Completed - Clinical trials for Rheumatoid Arthritis

Validation of Self-administered Questionnaire for Assessing Calcium Intake in Patients With Multiple Sclerosis or Chronic Inflammatory Arthritis

QALCIMUM
Start date: March 2016
Phase: N/A
Study type: Interventional

The main objective of this study is to measure, in patients with MS or Chronic Inflammatory Arthritis (CIA), the correlation between two calcium intake assessment methods: A self assessment questionnaire of calcium intake (QALCIMUM®) versus a food survey serving as a reference (gold standard) and based on data from CIQUAL *. * CIQUAL Data: Nutritional food composition table available on the website of the ANSES (National Agency for Sanitary Security of Food, Environment and Labour), published by the Observatory of the Nutritional Quality of Foods. This table includes 1500 sheets of 58 nutritional components. The data is integrated into the software (DATAMEAL) for calculating the ingesta parameters at the Nîmes University Hospital.

NCT ID: NCT02633332 Completed - Clinical trials for Rheumatoid Arthritis

Use of Well Known Drugs for New Destination - RA Improvement (RANT)

RANT
Start date: February 2015
Phase: Phase 1
Study type: Interventional

The purpose of this interventional study is to determine whether tetracyclines, statins, antiviral and Vitamin D3 in single subministration are effective in improvement of life and health condition in the treatment of rheumatoid arthritis due to autoimmune disease (RA) in all his forms, specially in patients intolerant to commonly used treatments.

NCT ID: NCT02632890 Completed - Clinical trials for Rheumatoid Arthritis

Assessment of the Effectiveness of IV and SC Abatacept (Orencia) Patient Alert Cards in Patients With Rheumatoid Arthritis in a Sample of EU Countries

Start date: November 29, 2016
Phase: N/A
Study type: Observational

The purpose of the study is to determine a) if the implementation of abatacept (Orencia®) patient alert card (PAC) resulted in effective understanding of key safety messages and b) if the degree of understanding of key safety messages is associated with improved clinical and safety outcomes.

NCT ID: NCT02629159 Active, not recruiting - Clinical trials for Rheumatoid Arthritis

A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Adults With Rheumatoid Arthritis Who Are on a Stable Dose of Methotrexate and Who Have an Inadequate Response to Methotrexate

SELECT-COMPARE
Start date: December 1, 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study was to assess efficacy, including inhibition of radiographic progression, and safety with upadacitinib versus placebo and versus an active comparator, adalimumab, in adults with with moderately to severely active rheumatoid arthritis (RA) who are on a stable background of methotrexate (MTX and who have an inadequate response to MTX.

NCT ID: NCT02628028 Terminated - Clinical trials for Rheumatoid Arthritis

A Study of LY3337641 in Rheumatoid Arthritis

RAjuvenate
Start date: August 22, 2016
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to evaluate the safety and effectiveness of LY3337641 in adults with rheumatoid arthritis (RA).

NCT ID: NCT02627924 Completed - Clinical trials for Rheumatoid Arthritis

Real-World Outcome of Rheumatoid Arthritis Patients in Korea on Adalimumab

ROCKA
Start date: November 18, 2015
Phase:
Study type: Observational

The study is designed as a prospective, observational study to assess the effect of adalimumab on health-related quality of life (QoL) and work productivity in patients with rheumatoid arthritis (RA) in Korea.

NCT ID: NCT02626026 Completed - Clinical trials for Rheumatoid Arthritis

Study to Evaluate Safety and Pharmacokinetics of GS-4059 (Tirabrutinib) in Healthy Volunteers and Participants With Rheumatoid Arthritis (RA)

Start date: January 26, 2016
Phase: Phase 1
Study type: Interventional

This study will consist of two parts: Part A will evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of tirabrutinib in healthy participants. Part B will evaluate the safety, tolerability, and the effect of tirabrutinib on disease-specific clinical markers and outcomes in participants with rheumatoid arthritis (RA).