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Risk Markers of Arterial Aging. The Paris Prospective Study III-2 — PPS3-2  

Arterial Stiffness Clinical Trial

Official title:
Risk Markers of Arterial Aging and Subsequent Risk of Cardiovascular Diseases and Beyond. The Paris Prospective Study III-2

Clinical Trial Summary

The main objectives of PPS3-2 are (i) to describe the dynamics of vascular aging and baroreflex sensitivity 12 to 16 years a part, (ii) to identify their determinants, and (iii) to quantify the subsequent risk of cardiovascular diseases.

Clinical Trial Description

Since May 2008, PPS3 is being following the CVD morbidity of 10157 healthy volunteers aged 50-75 years at baseline. In PPS3-2, we plan to re-invite survivors and volunteers of PPS3 to undergo a second physical examination. In particular, they will undergo a second high-precision carotid echotracking to measure vascular aging parameters and baroreflex sensitivity, permitting to study their respective dynamics. They will also underwent for the first time ultra fast echo of the radial artery to measure vascular aging parameters of the medium-sized arteries. According to fundings, blood samples will be taken and stored at -80°C in the whole population or in a subsample. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06079424
Study type Observational
Source Institut National de la Santé Et de la Recherche Médicale, France
Contact Jean-Philippe Empana, MD, PhD
Phone 33153988020
Email jean-philippe.empana@inserm.fr
Status Not yet recruiting
Phase
Start date June 2024
Completion date December 2037
View Details
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