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High Dose Candesartan Versus Quinapril for Restenosis Prophylaxis After Stent Angioplasty

Arterial Occlusive Diseases Clinical Trial

Clinical Trial Summary

The study is designed to test the hypothesis that high dose candesartan treatment compared to quinapril is able to reduce intima hyperproliferation and the restenosis rate after stent angioplasty in peripheral occlusive artery disease.

Clinical Trial Description

Patients are randomly assigned to treatment with either candesartan 32 mg/d or Quinapril 20 mg/d before the angioplasty. Walking distance, intima media thickness and crurobrachial pressure ratios are compared after 6 weeks, 3 months and 6 months. After 6 months an angiographic control is performed. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00154050
Study type Interventional
Source Technische Universität Dresden
Contact
Status Completed
Phase N/A
Start date May 2004
Completion date July 2006
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